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Table 3 Factors associated with the count of health-related risk factors in childhood cancer survivors vs. controls

From: Health-related risk behaviors among U.S. childhood cancer survivors: a nationwide estimate

Demographics

Risk behaviors (N = 1322)

Risk behaviors (N = 1479)

Risk behaviors (N = 1479)

1 risk behavior vs. none

 ≥ 1 risk behaviors vs. none

 ≥ 2 risk behaviors vs. ≤ 1

Univariate

Multivariable

Univariate

Multivariable

Univariate

Multivariable

OR (95% CI)

p-value

aOR (95% CI)

p-value

OR (95% CI)

p-value

aOR (95% CI)

p-value

OR (95% CI)

p-value

aOR (95% CI)

p-value

Demographic and socioeconomic factors

Group (CCS vs. Control)

1.08 (0.82, 1.41)

0.607

0.89 (0.66, 1.21)

0.465

1.30 (1.03, 1.66)

0.030

0.97 (0.73, 1.29)

0.850

2.35 (1.65, 3.35)

 < 0.001

1.33 (0.85, 2.09)

0.216

Education Level

  High school and below

Ref

 < 0.001

***

Ref

0.004**

Ref

 < 0.001

***

Ref

 < 0.001

***

Ref

 < 0.001

***

Ref

0.007

**

  Attended college or technical school

0.73 (0.51, 1.05)

0.84 (0.57, 1.24)

0.70 (0.51, 0.97)

0.84 (0.59, 1.19)

0.64 (0.40, 1.05)

0.75 (0.43, 1.30)

  College or technical school and above

0.38 (0.27, 0.53)

0.53 (0.36, 0.78)

0.32 (0.24, 0.44)

0.47 (0.33, 0.67)

0.22 (0.13, 0.38)

0.37 (0.20, 0.69)

Employment

  Employed/self-employed

Ref

0.020*

NA

Ref

 < 0.001

***

NA

Ref

 < 0.001

***

NA

  Out of work/A homemaker/A student

1.40 (0.92, 2.11)

1.31 (0.91, 1.88)

0.98 (0.56, 1.71)

  Retired

0.80 (0.46, 1.38)

0.71 (0.42, 1.21)

0.33 (0.09, 1.15)

  Unable to work

2.28 (1.19, 4.37)

2.91 (1.67, 5.08)

3.66 (1.80, 7.44)

Marital status

  Married/A member of an unmarried couple

Ref

 < 0.001

***

Ref

0.017*

Ref

 < 0.001

***

Ref

0.004

**

Ref

 < 0.001

***

Ref

0.120

  Divorced/widowed/separated

2.37 (1.65, 3.41)

1.73 (1.16, 2.59)

2.57 (1.85, 3.55)

1.85 (1.28, 2.66)

2.62 (1.57, 4.36)

1.92 (1.02, 3.64)

  Never married

1.22 (0.82, 1.83)

0.90 (0.58, 1.41)

1.37 (0.96, 1.96)

1.05 (0.70, 1.56)

1.46 (0.87, 2.47)

1.33 (0.72, 2.48)

Number of children in household (Ref. to No children)

  One or more

0.66 (0.46, 0.94)

0.023*

0.69 (0.46, 1.02)

0.062

0.78 (0.57, 1.06)

0.111

0.80 (0.56, 1.13)

0.200

1.29 (0.81, 2.05)

0.280

NA

Any healthcare coverage (Ref. to No)

  Yes

0.54 (0.33, 0.87)

0.011*

0.82 (0.49, 1.39)

0.459

0.56 (0.36, 0.87)

0.010*

0.85 (0.52, 1.39)

0.529

0.72 (0.39, 1.33)

0.289

NA

Annual household income

  Less than $15,000

Ref

 < 0.001

***

Ref

0.044

*

Ref

 < 0.001

***

Ref

0.011

*

Ref

 < 0.001

***

Ref

0.720

  $15,000 to less than $25,000

1.05 (0.56, 1.98)

1.31 (0.67, 2.55)

0.89 (0.51, 1.57)

1.08 (0.59, 1.96)

0.69 (0.31, 1.50)

1.13 (0.45, 2.82)

  $25,000 to less than $35,000

0.67 (0.35, 1.29)

0.93 (0.46, 1.86)

0.54 (0.30, 0.98)

0.76 (0.40, 1.43)

0.50 (0.21, 1.18)

0.90 (0.34, 2.38)

  $35,000 to less than $50,000

0.51 (0.27, 0.96)

0.79 (0.40, 1.55)

0.39 (0.22, 0.69)

0.65 (0.35, 1.20)

0.24 (0.10, 0.58)

0.63 (0.23, 1.74)

  $50,000 or more

0.31 (0.18, 0.53)

0.61 (0.33, 1.12)

0.23 (0.14, 0.38)

0.51 (0.29, 0.88)

0.22 (0.11, 0.43)

0.78 (0.32, 1.87)

Clinical factors

Days with poor mental health in past 30 days (Ref. to zero day)

  At least 1 day

1.50 (1.13, 2.00)

0.006

**

1.33 (0.97, 1.83)

0.083

1.85 (1.42, 2.39)

 < 0.001

***

1.52 (1.13, 2.03)

0.006

**

2.70 (1.75, 4.16)

 < 0.001

***

1.45 (0.86, 2.45)

0.166

Days with poor physical health in past 30 days (Ref. to zero day)

  At least 1 day

1.80 (1.34, 2.41)

 < .001

***

1.53 (1.10, 2.12)

0.011

*

1.98 (1.52, 2.59)

 < 0.001

***

1.43 (1.06, 1.95)

0.020

*

2.06 (1.35, 3.14)

 < 0.001

***

1.03 (0.60, 1.75)

0.924

Obesity (Ref. to No)

  Yes

1.21 (0.92, 1.60)

0.180

0.94 (0.69, 1.28)

0.692

1.31 (1.02, 1.69)

0.038

*

0.88 (0.67, 1.17)

0.381

1.39 (0.92, 2.11)

0.117

1.19 (0.73, 1.95)

0.481

Number of chronic health conditions (Ref. to none or 1)

  > 1

1.78 (1.30, 2.45)

 < .001

***

1.15 (0.79, 1.68)

0.452

2.38 (1.80, 3.16)

 < .001

***

1.39 (0.99, 1.95)

0.059

5.26 (3.25, 8.51)

 < .001

***

2.81 (1.51, 5.20)

0.001

**

  1. CCS Childhood cancer survivors, NA Not applicable covariate for not satisfying the variable selection criterium in the model fitting step
  2. *p < 0.05, **p < 0.01, ***p < 0.001