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Fig. 2 | BMC Cancer

Fig. 2

From: FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer

Fig. 2

FBXO28 overexpression promotes the viability of ovarian cancer cells. A. Left panel: The efficacy of FBXO28 knockdown was determined using Western blotting. Right panel: Corresponding quantitative analysis results. B. Left panel: The efficacy of FBXO28 overexpression was determined using Western blotting. Right panel: Corresponding quantitative analysis results. C. A CCK-8 assay showed that FBXO28 knockdown suppressed the viability of ovarian cancer cells. D. A CCK-8 assay showed that FBXO28 overexpression promoted the viability of ovarian cancer cells. E. Left panel: FBXO28 knockdown decreased the proliferation capacity of A2780 cells, as determined by a colony formation assay. Right panel: Corresponding quantitative analysis results. F. Left panel: FBXO28 overexpression increased the proliferation capacity of A2780 cells, as determined by a colony formation assay. Right panel: Corresponding quantitative analysis results. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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BMC Cancer

ISSN: 1471-2407

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