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Table 6 The results of the univariate and multivariate Cox regression analysis for disease-free survival

From: Prognostic value of GLIM-defined malnutrition in combination with hand-grip strength or gait speed for the prediction of postoperative outcomes in gastric cancer patients with cachexia

Factors

Univariable analysis

Multivariate analysis

OR (95%CI)

P

OR (95%CI)

P

GLIM-malnutrition

    

Yes/No

1.728 (1.145–2.607)

0.009*

1.815 (1.186–2.779)

0.006*

GLIM-malnutrition + low HGS

    

Yes/No

1.216 (0.864–1.710)

0.261

  

GLIM-malnutrition + low gait speed

    

Yes/No

1.760 (1.237–2.503)

0.002*

  

Age, years

    

≥ 75/<75

1.263 (0.868–1.838)

0.222

  

Gender

    

Males/females

1.126 (0.800-1.584)

0.495

  

BMI, kg/m2

    

< 18.5/≥18.5

1.573 (1.098–2.253)

0.014*

1.567 (1.021–2.406)

0.040*

Low albumin

    

Yes/No

1.635 (1.176–2.273)

0.003*

  

Anemia

    

Yes/No

1.563 (1.134–2.154)

0.006*

  

Charlson Comorbidity Index

    

1/0

0.749 (0.482–1.166)

0.201

  

≥ 2/0

1.048 (0.628–1.748)

0.858

  

Previous abdominal surgery

    

Yes/No

0.752 (0.448–1.262)

0.281

  

Tumor location

 

0.063

  

Medium/ Proximal

1.298 (0.731–2.306)

0.373

  

Distal/ Proximal

1.156 (0.696–1.920)

0.574

  

2/3 or more / Proximal

2.590 (1.223–5.487)

0.013*

  

Differentiation of tumor

    

Poorly /Well

2.630 (1.711–4.044)

< 0.001*

1.838 (1.184–2.854)

0.007*

TNM stage

 

< 0.001*

 

< 0.001*

II/I

1.901 (0.968–3.735)

0.062

1.522 (0.769–3.010)

0.228

III/I

5.817 (3.273–10.337)

< 0.001*

4.259 (2.363–7.678)

< 0.001*

Laparoscopy-assisted surgery

    

Yes/No

0.616 (0.423–0.898)

0.012*

  

Type of resection

    

Total/Subtotal

1.979 (1.432–2.736)

< 0.001*

1.513 (1.085–2.110)

0.015*

Combined organ resection

    

Yes/No

2.840 (1.804–4.472)

< 0.001*

2.434 (1.531–3.870)

< 0.001*

  1. HR Hazard ratio; CI Confidence interval; BMI, body mass index; SMI, skeletal muscle index; HGS, hand-grip strength; TNM, tumor–node–metastasis.
  2. * Statistically significant.