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Table 1 Baseline characteristics of patients

From: Prognostic value of GLIM-defined malnutrition in combination with hand-grip strength or gait speed for the prediction of postoperative outcomes in gastric cancer patients with cachexia

Characteristics

Total

(n = 356)

GLIM-defined malnutrition

(n = 269)

Non-malnutrition

(n = 87)

P

Age, median (IQR), years

66 (14)

68 (15.5)

62 (11)

< 0.001*

Gender

   

0.062

Female

122 (34.3%)

85 (31.6%)

37 (42.5%)

Male

234 (65.7%)

184 (68.4%)

50 (57.5%)

BMI, median (IQR), kg/m2

20.90 (2.22)

20.45 (2.21)

22.11 (1.98)

< 0.001*

Albumin, mean (SD), g/L

36.93 ± 4.97

36.42 ± 4.87

38.30 ± 4.96

< 0.001*

Hemoglobin, median (IQR), g/L

119.00 (15.75)

116.00 (16.00)

127.00 (13.00)

0.006*

Charlson Comorbidity Index

   

0.343

0

250 (70.2%)

185 (68.8%)

65 (74.7%)

1

68 (19.1%)

55 (20.4%)

13 (14.9%)

≥ 2

38 (10.7%)

29 (10.8%)

9 (10.4%)

Previous abdominal surgery

   

0.045*

Yes

47 (13.2%)

30 (11.2%)

17 (19.5%)

No

309 (86.8%)

239 (88.8%)

70 (80.5%)

Weight loss in the last 6 months (IQR), (%)

7.38 (4.69)

7.85 (4.28)

4.08 (3.81)

< 0.001*

L3 SMI, median (IQR), cm2/m2

39.66 (4.51)

39.57 (4.28)

40.23 (6.14)

0.081

SMD, median (IQR), HU

36.70 (4.30)

36.20 (4.85)

37.50 (5.50)

0.334

HGS, mean (SD), kg

24.90 ± 8.91

24.44 ± 8.94

26.34 ± 8.73

0.084

6-m gait speed, mean (SD), m/s

0.96 ± 0.23

0.94 ± 0.23

1.02 ± 0.22

0.004*

Tumor location

   

0.996

Proximal

48 (13.5%)

36 (13.4%)

12 (13.8%)

Medium

75 (21.1%)

56 (20.8%)

19 (21.8%)

Distal

218 (61.2%)

165 (61.3%)

53 (60.9%)

2/3 or more

15 (4.2%)

12 (4.5%)

3 (3.5%)

Differentiation of tumor

   

0.563

Poorly differentiated

249 (69.9%)

186 (69.1%)

63 (72.4%)

Well differentiated

107 (30.1%)

83 (30.9%)

24 (27.6%)

TNM stage

   

0.690

I

88 (24.7%)

61 (22.7%)

27 (31.0%)

II

85 (23.9%)

71 (26.4%)

14 (16.1%)

III

183 (51.4%)

137 (50.9%)

46 (52.9%)

Laparoscopy assisted surgery

   

0.371

Yes

117 (32.9%)

85 (31.6%)

32 (36.8%)

No

239 (67.1%)

184 (68.4%)

55 (63.2%)

Type of resection

   

0.128

Subtotal gastrectomy

201 (56.5%)

158 (58.7%)

43 (49.4%)

Total gastrectomy

155 (43.5%)

111 (41.3%)

44 (50.6%)

Combined organ resection

   

0.554

Yes

30 (8.4%)

24 (8.9%)

6 (6.9%)

No

326 (91.6%)

245 (91.1%)

81 (93.1%)

  1. IQR, interquartile range; SD, standard deviation; BMI, body mass index; L3, third lumbar vertebra; SMI, skeletal muscle index; SMD, skeletal muscle density; HU, Hounsfield unit; HGS, hand-grip strength; TNM, tumor–node–metastasis.
  2. The values in the table were number of patients and percent unless indicated otherwise.
  3. * Statistically significant compared with patients without malnutrition.
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BMC Cancer

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