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Fig. 4 | BMC Cancer

Fig. 4

From: The macrophage-associated prognostic gene ANXA5 promotes immunotherapy resistance in gastric cancer through angiogenesis

Fig. 4

High expression of ANXA5 promotes the progression of gastric cancer. (A) Immunohistochemistry results of ANXA5 in the Human Protein Atlas (HPA) database and tissue chips. (B) Expression levels of ANXA5 in gastric cancer cell lines and normal gastric mucosal epithelium (GES-1). (C) Silencing ANXA5 with small interfering RNA (siRNA) in SGC-7901. Scratch assay (D) and migration assay (E) as well as proliferation assay (F) results of SGC-7901 cells after ANXA5 silencing. (G) Silencing ANXA5 with small siRNA in EA.hy926 cells. (H) ANXA5 silencing inhibits angiogenesis. i: Quantitative statistical results of the corresponding experimental outcomes. **p < 0.01; ***p < 0.001. Full-length gels are presented in Supplementary Fig. 5

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