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Table 3 Multivariate analysis of prognostic factor for lung adenocarcinoma brain metastases patients

From: Spatial and temporal heterogeneity of tumor immune microenvironment between primary tumor and brain metastases in NSCLC

Characteristics

Total(N)*

Multivariate analysis

HR (95% CI)

P value

Age at diagnosis (years)

  

<60

18

Reference

 

≥ 60

25

1.148 (0.434–3.036)

0.781

stage at diagnosis

  

I-III

7

Reference

 

IV

36

0.427 (0.136–1.345)

0.146

B7-H4

   

low

27

Reference

 

high

16

3.276 (1.335–8.041)

0.010

IDO1

   

low

23

Reference

 

high

20

1.719 (0.683–4.326)

0.250

CD68

   

low

22

Reference

 

high

21

3.775 (1.419–10.044)

0.008

  1. Indicators with P values in bold were independent prognostic factor for lung adenocarcinoma brain metastases patients
  2. * Because the “stage at diagnosis” of 7 patients was unknown, only 43 patients were finally included in the multivariate analysis