Automated evaluation of masseter muscle volume: deep learning prognostic approach in oral cancer

BMC Cancer

Table 4 Univariate and multivariate analyses of the low AIMMV group

Variables		Univariate analysis		Multivariate analysis
		(Fisher’s exact test)		(Cox proportional hazards model)
	Cutoff	HR	p-value	HR	p-value
	Cutoff	(95% CI)	p-value	(95% CI)	p-value
Age	77	2.018	0.068
Age	77	(0.919–4.268)	0.068
Sex	Male or female	0.927	0.871
Sex	Male or female	(0.468–1.857)	0.871
Stage	I and II or III and IV	10.875	< 0.001	6.267	< 0.001
Stage	I and II or III and IV	(4.714–28.304)	< 0.001	(2.785–14.100)	< 0.001
CRP (mg/dL)	1.15	3.259	0.021	0.733	0.615
CRP (mg/dL)	1.15	(1.044–9.314)	0.021	(0.219–2.454)	0.615
Alb (g/dL)	4.3	2.090	0.035	0.704	0.374
Alb (g/dL)	4.3	(1.041–4.329)	0.035	(0.325–1.525)	0.374
A/G ratio	1.58	3.015	0.004	1.258	0.621
A/G ratio	1.58	(1.315–7.802)	0.004	(0.507–3.122)	0.621
T-cho (mg/dL)	143	1.504	0.510
T-cho (mg/dL)	143	(0.349–4.984)	0.510
mGPS	2	12.55	0.005	2.942	0.169
mGPS	2	(1.736–143.109)	0.005	(0.632–13.710)	0.169
CONUT	2	4.682	< 0.001	2.093	0.040
CONUT	2	(2.143–10.115)	< 0.001	(1.035–4.229)	0.040
CAR	0.033	2.703	0.065
CAR	0.033	(0.920–10.839)	0.065
NLR	2.398	2.676	0.003	0.995	0.988
NLR	2.398	(1.337–5.496)	0.003	(0.485–2.039)	0.988
PLR	189.507	1.493	0.263
PLR	189.507	(0.688–3.114)	0.263
PNI	53.888	3.428	0.005	1.619	0.405
PNI	53.888	(1.371–10.281)	0.005	(0.521–5.028)	0.405
BMI (kg/m²)	20.233	3.375	< 0.001	2.044	0.023
BMI (kg/m²)	20.233	(1.680–6.959)	< 0.001	(1.102–3.793)	0.023
AIMMV (cm³)	Male, 45.030		< 0.001		0.036
	Male, 45.030	4.346		2.231
	Female, 31.752	(2.042–9.946)		(1.055–4.719)

Low AIMMV was an independent poor prognostic factor, along with stage, CONUT score, and BMI (HR, 2.231; 95% CI, 1.055–4.719; p = 0.036)

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