Automated evaluation of masseter muscle volume: deep learning prognostic approach in oral cancer

BMC Cancer

Table 3 Univariate and multivariate analyses in the low MMV group

Variables		Univariate analysis		Multivariate analysis
		(Fisher’s exact test)		(Cox proportional hazards model)
	Cutoff	HR	p-value	HR	p-value
	Cutoff	(95% CI)	p-value	(95% CI)	p-value
Age	77	2.018	0.068
Age	77	(0.919–4.268)	0.068
Sex	Male or female	0.927	0.871
Sex	Male or female	(0.468–1.857)	0.871
Stage	I and II or III and IV	10.875	< 0.001	5.631	< 0.001
Stage	I and II or III and IV	(4.714–28.304)	< 0.001	(2.477–12.800)	< 0.001
CRP (mg/dL)	1.15	3.259	0.021	0.659	0.501
CRP (mg/dL)	1.15	(1.044–9.314)	0.021	(0.196–2.220)	0.501
Alb (g/dL)	4.3	2.090	0.035	0.582	0.183
Alb (g/dL)	4.3	(1.041–4.329)	0.035	(0.262–1.292)	0.183
A/G ratio	1.58	3.015	0.004	1.249	0.617
A/G ratio	1.58	(1.315–7.802)	0.004	(0.522–2.987)	0.617
T-cho (mg/dL)	143	1.504	0.510
T-cho (mg/dL)	143	(0.349–4.984)	0.510
mGPS	2	12.550	0.005	2.516	0.238
mGPS	2	(1.736–143.109)	0.005	(0.543–11.650)	0.238
CONUT	2	4.682	< 0.001	1.872	0.094
CONUT	2	(2.143–10.115)	< 0.001	(0.898–3.904)	0.094
CAR	0.033	2.703	0.065
CAR	0.033	(0.920–10.839)	0.065
NLR	2.398	2.676	0.003	1.028	0.939
NLR	2.398	(1.337–5.496)	0.003	(0.502–2.108)	0.939
PLR	189.51	1.493	0.263
PLR	189.51	(0.688–3.114)	0.263
PNI	53.888	3.428	0.005	1.857	0.273
PNI	53.888	(1.371–10.281)	0.005	(0.615–5.609)	0.273
BMI (kg/m²)	20.233	3.375	< 0.001	2.055	0.022
BMI (kg/m²)	20.233	(1.680–6.959)	< 0.001	(1.108–3.812)	0.022
MMV (cm³)	Male, 45.030		< 0.001		< 0.001
	Male, 45.030	8.789		4.325
	Female, 31.752	(4.078–20.350)		(2.082–8.981)

Low MMV was an independent poor prognostic factor, along with stage and BMI (HR, 4.325; 95% CI, 2.082–8.981; p < 0.001)

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