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Table 6 Associations between chemotherapy regimen and b-pCR in different subgroups

From: Real-world data on neoadjuvant chemotherapy with dual-anti HER2 therapy in HER2 positive breast cancer

Combined group

THP

Stratification by chemotherapy regimens

AC-THP

TCbHP

ER Status

 ER-Negative

Ref

2.916 (1.539–5.527)*

2.238 (0.652–7.679)

 ER-Positive

Ref

1.929 (0.608–5.527)

2.307 (0.516–10.307)

PR Status

 PR-Negative

Ref

2.500 (1.401–4.461)*

2.123 (0.772–5.842)

 PR-Positive

Ref

3.019 (0.299–30.424)

4.809 (0.364–63.564)

HER2 Status

 2 + 

Ref

0.766 (0.101–5.810)

0.842 (0.111–6.382)

 3 + 

Ref

2.697 (1.512–4.812)*

2.771 (0.978–7.857)

Ki-67 index

 < 30%

Ref

0.918 (0.156–5.389)

0.722 (0.053–9.810)

 ≥ 30%

Ref

2.672 (1.521–4.695)*

3.544 (1.353–9.339)*

  1. *represents p < 0.05