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Table 5 Associations between chemotherapy regimen and t-pCR in different subgroups

From: Real-world data on neoadjuvant chemotherapy with dual-anti HER2 therapy in HER2 positive breast cancer

Combined group

THP

Stratification by chemotherapy regimens

AC-THP

TCbHP

ER Status

 ER-Negative

Ref

2.521 (1.266–5.022)*

1.867 (0.504–6.915)

 ER-Positive

Ref

1.136 (0.384–3.365)

1.828 (0.429–7.791)

PR Status

 PR-Negative

Ref

2.194 (1.184–4.065)*

1.791 (0.691–5.185)

 PR-Positive

Ref

1.009 (0.172–7.036)

2.816 (0.332–23.859)

HER2 Status

 2 + 

Ref

0.395 (0.052–2.978)

0.485 (0.065–3.628)

 3 + 

Ref

2.307 (1.259–4.226)*

3.267 (1.051–10.158)*

Ki-67 index

 < 30%

Ref

0.701 (0.131–3.738)

0.745 (0.057–9.702)

 ≥ 30%

Ref

2.215 (1.233–3.979)*

3.927 (1.381–11.172)*

  1. *represents p < 0.05