Table 1 Baseline characteristics of patients
Characteristics | Upfront RT(n = 91) N (%) | Deferred RT(n = 72) N (%) | χ2 | P |
|---|---|---|---|---|
Sex | 1.538 | 0.215 | ||
Male | 39(42.9) | 24(33.3) | ||
Female | 52(57.1) | 48(66.7) | ||
Age | 0.835 | 0.361 | ||
< 60 | 44(48.4) | 40(55.6) | ||
≥ 60 | 47(51.6) | 32(44.4) | ||
KPS | 2.446 | 0.118 | ||
< 80 | 40(44.0) | 23(31.9) | ||
≥ 80 | 51(56.0) | 49(68.1) | ||
Symptomatic BM | 0.012 | 0.911 | ||
NO | 26(28.6) | 20(27.8) | ||
YES | 65(71.4) | 52(72.2) | ||
Initial BM | 30.910 | < 0.001 | ||
NO | 17(18.7) | 44(61.1) | ||
YES | 74(81.3) | 28(38.9) | ||
RT pattern | 2.766 | 0.251 | ||
WBRT | 31(34.0) | 32(44.4) | ||
LCRT | 30(33.0) | 24(33.3) | ||
WBRT + LCRT | 30(33.0) | 16(22.3) | ||
Lung-molGPA | 0.001 | 0.974 | ||
1-2.5 | 44(48.4) | 35(48.6) | ||
3–4 | 47(51.6) | 37(51.4) | ||
Gene-mutation type | 1.050 | 0.306 | ||
EGFR mutation | 84(92.3) | 63(87.5) | ||
19 | 41(45.0) | 19(26.4) | ||
21 | 37(40.7) | 30(41.7) | ||
others | 6(6.6) | 14(19.4) | ||
ALK rearrangements | 7(7.7) | 9(12.5) | ||
Generation of TKI | 2.695 | 0.101 | ||
First generation | 28(30.8) | 14(19.4) | ||
Second and third generation | 63(69.2) | 58(80.6) | ||
Metastases | 2.328 | 0.127 | ||
Oligometastases | 45(49.5) | 27(37.5) | ||
Polymetastases | 46(50.5) | 45(62.5) | ||
Extracranial disease | 4.590 | 0.032 | ||
NO | 57(62.6) | 33(45.8) | ||
YES | 34(37.4) | 39(54.2) | ||
BM diameter | 1.189 | 0.275 | ||
< 2 cm | 44(48.4) | 41(56.9) | ||
≥ 2 cm | 47(51.6) | 31(43.1) | ||
BM number | 2.508 | 0.113 | ||
≤ 3 | 48(52.7) | 29(40.3) | ||
> 3 | 43(47.3) | 43(59.7) |