Table 2 Top 12 GO terms and KEGG pathways associated with the 62 genes identified via DAVID analysis
Term | Count | P-value | Genes |
|---|---|---|---|
embryonic skeletal system morphogenesis | 4 | 2.65E-04 | HOXB3, HOXB7, HOXB6, HOXB5 |
angiogenesis | 6 | 7.36E-04 | EPGN, EGF, MCAM, SERPINE1, NRXN3, HOXB3 |
anterior/posterior pattern specification | 4 | 0.002168409 | HOXB3, HOXB7, HOXB6, HOXB5 |
sequence-specific DNA binding | 7 | 0.004101735 | TFAP2A, SALL2, SHOX2, HOXB3, PITX2, HOXB7, HOXB6 |
platelet degranulation | 4 | 0.004431234 | ITIH3, EGF, SERPINE1, CD9 |
growth factor activity | 4 | 0.012227549 | EPGN, BDNF, EGF, LIF |
presynaptic membrane | 3 | 0.015587105 | RIMS1, GRIK2, SYT7 |
p53 signaling pathway | 3 | 0.022469123 | PIDD1, GADD45A, SERPINE1 |
negative regulation of transcription from RNA polymerase II promoter | 7 | 0.027411597 | TFAP2A, TBX15, SALL2, SHOX2, ANKRD1, HOXB3, PITX2 |
regulation of protein localization to cell surface | 2 | 0.028579562 | BDNF, EGF |
positive regulation of epidermal growth factor-activated receptor activity | 2 | 0.028579562 | EPGN, EGF |
anatomical structure morphogenesis | 3 | 0.03534194 | KRT18, MCAM, HOXB5 |