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Fig. 1 | BMC Cancer

Fig. 1

From: Sequential gene expression analysis of myelodysplastic syndrome transformation identifies HOXB3 and HOXB7 as the novel targets for mesenchymal cells in disease

Fig. 1

Heatmaps, Volcano plots of the DEGs in three datasets and the intersections of DEGs between groups. (A) Heatmap of the dysregulated RNA expression profiles in HD and MDS patients. 477 DEGs in GSE170490, 330 DEGs in GSE61853 and 660 DEGs in GSE140101. (B) Volcano plots of the DEGs in GSE140101, GSE107490 and GSE16853 cohorts. Red points: significantly upregulated DEGs, blue points: significantly downregulated DEGs. (C)PCA of RNA-seq data from HD-MSC and MDS-MSC (n = 13 and n = 18, respectively), Each symbol represents one sample. (D) Venn diagram of the DEGs in MDS/HD among GSE107490, GSE61853 and GSE140101 and the DEGs in MDS/HD between DEGs of different 2 groups in the 3 GSE

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BMC Cancer

ISSN: 1471-2407

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