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Table 1 Disparities in clinicopathological features amongst patients with the high and limited nodal burden

From: Diagnostic value of applying preoperative breast ultrasound and clinicopathologic features to predict axillary lymph node burden in early invasive breast cancer: a study of 1247 patients

Variables

Total

(n = 1274)

Limited nodal burden(%) (n = 1044)

High nodal burden (%) (n = 230)

χ2

P值

Age

   

0.104

0.748

 ≤ 50

466

384(36.8)

82(35.7)

  

 >50

808

660(63.2)

148(64.3)

  

Marital status

   

0.001

0.977

 Unmarried

8

5(0.5)

3(1.3)

  

 Married

1266

1039(99.5)

227(98.7)

  

Fertility status

   

0.084

0.773

 No

27

16(1.5)

11(4.8)

  

 Yes

1247

1028(98.5)

219(95.2)

  

Menopause

   

2.138

0.144

 No

522

449(43.0)

73(31.7)

  

 Yes

752

595(57.0)

157(68.3)

  

Histologic grade

   

1.233

0.267

 I级

149

127(12.2)

22(9.6)

  

 II-III级

1125

917(87.8)

208(90.4)

  

Ki-67

   

7.500

0.006

 Negative

425

366(35.1)

59(25.7)

  

 Positive

849

678(64.9)

171(74.3)

  

P53

   

0.303

0.582

 Negative

407

330(31.6)

77(33.5)

  

 Positive

867

714(68.4)

153(66.5)

  

ER

   

0.123

0.726

 Negative

333

275(26.3)

58(25.2)

  

 Positive

941

769(73.7)

172(74.8)

  

PR

   

0.044

0.833

 Negative

419

342(32.8)

77(33.5)

  

 Positive

855

702(67.2)

153(66.5)

  

HER-2

   

1.073

0.300

 Negative

873

722(69.2)

151(65.7)

  

 Positive

401

322(30.8)

79(34.3)

  

MS

   

11.044

0.011

 Luminal A

365

317(30.4)

48(20.9)

  

 Luminal B

591

464(44.4)

127(55.2)

  

 Her-2 overexpression

140

114(10.9)

26(11.3)

  

 TN

178

149(14.3)

29(12.6)

  

Location

   

11.008

0.012

 lower inner quadrant

71

60(5.8)

11(4.8)

  

 upper outer quadrant

685

545(52.2)

140(60.9

  

 lower outer quadrant

198

158(15.1)

40(17.3)

  

 upper inner quadrant

320

281(26.9)

39(17.0)

  
  1. EBC Early-stage breast cancer, ER Estrogen-receptor, PR Progesterone-receptor, HER-2 Human epidermal growth factor receptor 2, MS Molecular subtype, TN Triple negative