Enrichment of colibactin-associated mutational signatures in unexplained colorectal polyposis patients

BMC Cancer

Table 2 Results of fecal pks using metagenomics and mutational signatures SBS88 and ID18 using WGS

ID	%	WGS SBS88	WGS ID18	Fecal pks
7	0	0/2	0/2	No
21	0	0/1	0/1	No
22	0	0/2	0/2	No
23	0	1/2	0/2	Yes
24	0	0/2	0/2	No
26	0	0/2	0/2	No
27	0	0/1	0/1
28	0	0/2	0/2	Yes
29	0	0/2	0/2	No
1	28.6	1/2	0/2	Yes
5	30.0	0/2	0/2
4	33.3	0/2	0/2	Yes
11	33.3			No
15	33.3	0/2	0/2	Yes
18	33.3	1/3	1/3	Yes
6	50.0	2/3	0/3	No
9	50.0	1/2	0/2	Yes
12	50.0	0/1	0/1
17	50.0	0/2	0/2	Yes
19	50.0	0/3	0/3
20	50.0	0/4	0/4	Yes
13	66.7	0/1	0/1	No
16	66.7	0/2	0/2	No
8	75.0	1/1	0/1	Yes
10	80.0	2/2	0/2	No
3	85.7			No
2	100.0	0/3	0/3	Yes
14	100.0	0/3	1/3	No
25	100.0	0/3	0/3	Yes

% - percentage of adenomas or carcinomas tested with NGS with a colibactin variant, WGS SBS88– number of samples with SBS88 / number of samples tested, WGS ID18– number of samples with ID18 / number of samples tested, Fecal pks– Yes for patients with and no for patients without pks in their feces sample

ISSN: 1471-2407