CNN-based multi-modal radiomics analysis of pseudo-CT utilization in MRI-only brain stereotactic radiotherapy: a feasibility study

Table 2 DVH comparisons between the Initial dose and the synthetic dose maps for OARs and PTV

DVH Feature		Initial CT		T1W		MAD			P value
DVH Feature		N = 34	N = 30	N = 34	N = 30	①	②	③	T1W	T1W-CE
PTV	D_min(Gy) / PD	0.85	0.84	0.84	0.84	0.01	0.00	0.00	0.538	0.523
	D_max(Gy) / PD	1.18	1.18	1.18	1.18	0.00	0.00	0.00	0.995	0.995
	D_mean(Gy) / PD	1.09	1.09	1.09	1.09	0.00	0.00	0.00	0.879	0.879
	R_50%	4.29	4.25	4.09	4.07	0.20	0.18	0.02	0.536	0.536
	R_100%	1.31	1.32	1.26	1.25	0.05	0.07	0.01	0.519	0.519
D_max(Gy) 0.1 cm³	Lens_L	22.63	15.16	21.84	13.67	0.79	1.49	-0.05	0.621	0.621
	Lens_R	18.04	14.62	17.23	14.10	0.81	0.52	0.02	0.950	0.950
	Opt_Chiasm	69.52	61.27	63.40	52.14	6.12	9.13	-0.05	0.648	0.648
	Opt_Nerve_L	73.83	63.41	73.68	64.48	0.15	-1.07	-0.05	0.956	0.956
	Opt_Nerve_R	54.82	43.59	57.04	45.31	-2.22	-1.72	0.11	0.931	0.961
	Spinal Cord	52.45	44.28	52.19	42.87	0.26	1.41	-0.12	0.893	0.893
	Brainstem	353.54	358.28	355.23	359.15	-1.69	-0.87	-0.21	0.971	0.971
D50%(Gy)	Brain-GTV	76.94	68.48	78.26	69.37	-1.32	-0.89	-0.05	0.917	0.917

Note: DVH features are expressed as mean values, and the shaded region in the MAD comparison plot represents data from only 30 patients. ① = CT vs. T1W; ② = CT vs. T1W-CE; ③ = T1W vs. T1W-CE. PD = prescribed dose; Lens_L = left lens; Lens_R = right lens; Opt_Chiasm = optic chiasm; Opt_Nerve_L = left optic nerve; Opt_Nerve_R = right optic nerve; Brain-GTV = normal brain

ISSN: 1471-2407