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Fig. 5 | BMC Cancer

Fig. 5

From: NUSAP1 promotes pancreatic ductal adenocarcinoma progression by drives the epithelial-mesenchymal transition and reduces AMPK phosphorylation

Fig. 5

NUSAP1 expression is increased in PDAC tissues. a Representative images of IHC staining for NUSAP1 in TMAs (scale bar, 200 μm; inset scale bar, 40 μm). b NUSAP1 expression in PDAC and adjacent normal tissues, as determined by the IHC score (n = 102, Student’s t test, P < 0.001). c Box plot analyses comparing the expression levels of NUSAP1 in patient PDAC tissues (red, n = 179) and normal tissues (gray, n = 171) in the GEPIA database (Student’s t test, P < 0.05). d The OS of patients with PDAC from our center was assessed using Kaplan–Meier analysis based on NUSAP1 expression (n = 160, log-rank test, P = 0.0086). (e) OS analyses of PDAC patients according to the expression of NUSAP1 (high versus low) in the GEPIA database (n = 178, log-rank test, P = 0.0046)

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