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Fig. 1 | BMC Cancer

Fig. 1

From: NUSAP1 promotes pancreatic ductal adenocarcinoma progression by drives the epithelial-mesenchymal transition and reduces AMPK phosphorylation

Fig. 1

NUSAP1 was among the top 10 key genes in PDAC. a Volcano plots of DEGs in each GEO dataset were drawn using GEO2R. Red represents the genes that were significantly upregulated, and blue represents the downregulated genes in PDAC samples. Black dots represent the genes that were not significantly upregulated or downregulated in PDAC samples. b The Venn diagram shows the number of common upregulated and downregulated DEGs shared by the three GEO datasets. c STRING PPI network of common DEGs identified from three GEO datasets. d Subnetwork of the top 10 hub genes from the PPI network using Cytoscape software. e Perturbation effects of the hub genes on 44 PDAC cell lines. f Information on the genetic alterations of the hub genes

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BMC Cancer

ISSN: 1471-2407

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