Table 2 Suggested dose constraints of organs at risk
Conventional fractionated RT (50 Gy in 25 fractions) | Hypofractionated RT (42.56 Gy in 16 fractions) | |||
|---|---|---|---|---|
required | acceptable | required | acceptable | |
Heart(Left_sided) | Dmean ≦ 6 Gy | Dmean ≦ 8 Gy | Dmean ≦ 5.1 Gy | Dmean ≦ 6.8 Gy |
V20Gy ≦ 5% | V25Gy ≦ 5% | V17Gy ≦ 5% | V21Gy ≦ 5% | |
Heart(Right_sided) | Dmean ≦ 2 Gy | Dmean ≦ 3 Gy | Dmean ≦ 1.7 Gy | Dmean ≦ 2.6 Gy |
V20Gy ≦ 0% | V25Gy ≦ 0% | V17Gy ≦ 0% | V21Gy ≦ 0% | |
Ipsilateral Lung | V20Gy ≦ 30% | V20Gy ≦ 35% | V17Gy ≦ 30% | V17Gy ≦ 35% |
V5Gy ≦ 60% | V5Gy ≦ 70% | V4.2 Gy ≦ 60% | V4.2 Gy ≦ 70% | |
Contralateral lung | V5Gy ≦ 10% | V5Gy ≦ 15% | V4.2 Gy ≦ 10% | V4.2 Gy ≦ 15% |
Contralateral breast | V5Gy ≦ 10% | V5Gy ≦ 15% | V4.2 Gy ≦ 10% | V4.2 Gy ≦ 15% |
Thyroid | Dmean ≦ 25 Gy | Dmean ≦ 26.2 Gy | Dmean ≦ 21.2 Gy | Dmean ≦ 22.2 Gy |
Esophagus | V20Gy ≦ 10% | V20Gy ≦ 15% | V17Gy ≦ 10% | V17Gy ≦ 15% |
Spinal cord | Dmax ≦ 45 Gy | Dmax ≦ 38.2 Gy | ||
Humeral head | Dmean ≦ 25 Gy | Dmean ≦ 26.2 Gy | Dmean ≦ 21.2 Gy | Dmean ≦ 22.2 Gy |
V30Gy ≦ 30% | V30Gy ≦ 35% | V28.5 Gy ≦ 30% | V28.5 Gy ≦ 35% | |
Brachial plexus | Dmax ≦ 54 Gy | Dmax ≦ 56.7 Gy | Dmax ≦ 46 Gy | Dmax ≦ 48.3 Gy |