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Table 3 Clinicopathologic characteristics of patients with < 12 LNs stratified by treatment

From: The effects of oxaliplatin-based adjuvant chemotherapy in high-risk stage II colon cancer with mismatch repair-deficient: a retrospective study

Population characteristics

Surgery alone

(N = 29)

Oxaliplatin-based

(N = 12)

P value

Age (years)

  

0.336

 ≥ 65

11(37.9)

2(16.7)

 

 < 65

18(62.1)

10(83.3)

 

Gender

  

0.254

 Male

9(31.0)

1(8.3)

 

 Female

20(69.0)

11(91.7)

 

Family history

  

1.000

 Yes

10(34.5)

4(33.3)

 

 No

19(65.5)

8(66.7)

 

Tumor site

  

0.755

 Right colon

13(44.8)

4(33.3)

 

 Left colon

11(37.9)

5(41.7)

 

 Multiple primary colorectal

5(17.2)

3(25.0)

 

pT4 category

  

0.288

 Yes

10(34.5)

7(58.3)

 

 No

19(65.5)

5(41.7)

 

LVI

  

0.969

 Yes

3(10.3)

2(16.7)

 

 No

26(89.7)

10(83.3)

 

PNI

  

1.000

 Yes

5(17.2)

2(16.7)

 

 No

24(82.8)

10(83.3)

 

Histological grade

  

0.938

 Poorly differentiated

10(34.5)

5(41.7)

 

 Moderately differentiated

19(65.5)

7 (58.3)

 

Pre-CEA

  

0.577

 Abnormal (> 5 ng/ml)

9(31.0)

2(16.7)

 

 Normal

20(69.0)

10(83.3)

 

Multiple risk feature

  

0.183

 Yes

19(65.5)

11(91.7)

 

 No

10(34.5)

1(8.3)

 
  1. Abbreviations < 12 LNs Fewer than twelve lymph nodes harvested, LVI Lymphatic vascular invasion, PNI Perineural invasion, Pre-CEA Preoperative carcinoembryonic antigen