Table 2 Clinicopathologic characteristics of pT4 patients stratified by treatment
Population characteristics | Surgery alone (N = 22) | Oxaliplatin-based (N = 24) | P-value |
|---|---|---|---|
Age (years) | 0.052 | ||
≥ 65 | 8(36.4) | 2(8.3) | |
< 65 | 14(63.6) | 22(91.7) | |
Gender | 0.840 | ||
Male | 4(18.2) | 6(25.0) | |
Female | 18(81.8) | 18(75.0) | |
Family history | 1.000 | ||
Yes | 11(50.0) | 12(50.0) | |
No | 11(50.0) | 12(50.0) | |
Tumor site | 0.416 | ||
Right colon | 13(59.1) | 12(50.0) | |
Left colon | 8(36.4) | 8(33.3) | |
Multiple primary colorectal | 1(4.5) | 4(16.7) | |
Lymphatic node number | 0.402 | ||
< 12 LNs | 10(45.5) | 7(29.2) | |
≥ 12 LNs | 12(54.5) | 17(70.8) | |
LVI | 0.129 | ||
Yes | 1(4.5) | 6(25.0) | |
No | 21(95.5) | 18(75.0) | |
PNI | 0.900 | ||
Yes | 4(18.2) | 3(12.5) | |
No | 18(81.8) | 21(87.5) | |
Histological grade | |||
Poorly differentiated | 12(54.5) | 12(50.0) | 0.990 |
Moderately differentiated | 10(45.5) | 12(50.0) | |
Pre-CEA | 0.606 | ||
Abnormal (> 5 ng/ml) | 8(36.4) | 6(25.0) | |
Normal | 14(63.6) | 18(75.0) | |
Multiple risk factors | 0.702 | ||
Yes | 19 (86.4) | 19 (79.2) | |
No | 3(13.6) | 5 (20.8) |