Table 3 Univariate and multivariate analysis of prognostic factors for PFS in newly diagnosed patients with DLBCL

Sex (male vs. female)

1.11

0.87–1.42

0.408

Age (> 60 vs. ≤60)

1.16

0.90–1.48

0.248

Ann Arbor Stage (III–IV vs. I–II)

2.66

1.96–3.60

< 0.001

1.71

1.21–2.43

0.003

Extranodal disease (>1 vs. ≤1)

2.18

1.71–2.77

< 0.001

1.49

1.14–1.95

0.003

ECOG score (2–4 vs. 0–1)

2.00

1.54–2.60

< 0.001

1.44

1.09–1.91

0.011

LDH (>ULN vs. normal)

2.15

1.68–2.75

< 0.001

1.41

1.06–1.87

0.019

B symptoms (present vs. absent)

1.64

1.27–2.12

< 0.001

1.13

0.85–1.50

0.421

Serum ApoA1 (high vs. low)

0.62

0.48–0.78

< 0.001

0.98

0.75–1.29

0.902

Subtype (non-GCB vs. GCB)

1.76

1.33–2.33

< 0.001

1.47

1.18–1.84

0.001

Regimen (CHOP-like vs. R-CHOP-like)

1.58

1.16–2.15

0.004

1.75

1.28–2.39

< 0.001