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Table 4 Pre- to post-exercise training changes to body composition, resting cardiovascular measurements, cardiorespiratory and functional fitness, and quality of life

From: The effects of short-term, progressive exercise training on disease activity in smouldering multiple myeloma and monoclonal gammopathy of undetermined significance: a single-arm pilot study

Variable

Pre-exercise training

Post-exercise training

Pre- to post-exercise training change

P statistic

Effect size

Body composition

     

Body mass (kg)

80.4 ± 31.4

80.6 ± 28.0

−0.5 ± 2.4

0.871

0.0

Body mass index (kg/m2)

27.3 ± 8.7

27.1 ± 9.0

−0.2 ± 0.8

0.759

0.0

Waist circumference (cm)

98.2 ± 29.3

93.8 ± 20.9

−2.8 ± 5.3

0.014

0.2

Hip circumference (cm)

103.9 ± 15.6

101.6 ± 16.6

−0.7 ± 3.0

0.070

0.1

Body fat percentage (%, N = 14)

30.4 ± 10.0

32.1 ± 10.6

0.2 ± 1.6

0.924

0.0

Fat mass (kg, N = 14)

20.9 ± 18.3

21.9 ± 19.4

0.2 ± 2.2

0.952

−

Lean soft-tissue mass (kg, N = 14)

58.8 ± 17.9

58.6 ± 17.8

−0.1 ± 1.0

0.818

0.0

Bone mineral density (g/cm2, N = 14)

1.18 ± 0.22

1.20 ± 0.22

0.00 ± 0.02

0.866

0.0

Bone mineral density T score (N = 14)

0.05 ± 2.60

0.15 ± 2.40

−0.05 ± 0.20

0.640

0.0

Resting cardiovascular measurements

Systolic blood pressure (mmHg)

142 ± 18

132 ± 17

−4 ± 14

0.293

0.1

Diastolic blood pressure (mmHg)

86 ± 11

81 ± 10

−3 ± 5

0.033

0.4

Resting heart rate (beats/min)

67 ± 6

65 ± 7

−3 ± 7

0.014

0.4

Cardiorespiratory and functional fitness

V̇O2PEAK (mL/kg/min, N = 12)

26.2 ± 4.5

26.0 ± 4.5

0.1 ± 2.7

0.601

0.1

Peak work-rate (METs, N = 12)

9.9 ± 3.1

14.9 ± 4.0

3.8 ± 2.8

0.001

1.4

Ventilatory threshold (mL/kg/min, N = 12)

18.1 ± 2.9

17.8 ± 3.1

−1.3 ± 2.1

0.569

0.1

8ft up-and-go (s, N = 12)

5.6 ± 1.3

4.6 ± 1.0

−0.8 ± 0.9

0.006

0.8

Sit-to-stand (number in 30s, N = 12)

13 ± 3

17 ± 4

5 ± 5

0.002

1.2

Grip strength (kg, N = 14)

30.1 ± 12.9

34.5 ± 15.2

2.0 ± 4.0

0.008

−

Upper limb flexibility (cm, N = 14)

−3.4 ± 9.8

−3.6 ± 12.7

0.8 ± 1.5

0.101

−

Lower limb flexibility (cm, N = 13)

7.8 ± 15.0

11.9 ± 7.6

5.7 ± 7.7

0.044

0.5

Quality of life

     

Satisfaction with life scale

24 ± 11

25 ± 9

1 ± 6

0.202

0.3

FACIT-fatigue scale

5 ± 9

2 ± 11

0 ± 5

0.640

0.1

PSQI

6 ± 5

5 ± 5

0 ± 4

0.900

0.0

SF-36 Physical function (%)

90 ± 30

95 ± 18

5 ± 10

0.022

−

SF-36 Physical role limitation (%)

100 ± 13

100 ± 0

0 ± 13

0.594

−

SF-36 Emotional role limitation (%)

100 ± 0

100 ± 0

0 ± 0

0.999

−

SF-36 Energy and fatigue (%)

65 ± 38

75 ± 23

10 ± 15

0.026

0.5

SF-36 Emotional wellbeing (%)

84 ± 22

84 ± 22

4 ± 12

0.285

0.2

SF-36 Social functioning (%)

88 ± 13

100 ± 19

0 ± 13

0.364

0.2

SF-36 Pain (%)

80 ± 23

90 ± 26

10 ± 15

0.272

−

SF-36 General health (%)

55 ± 15

55 ± 28

0 ± 8

0.342

0.1

  1. Data are median ± IQR. N = 15 unless otherwise stated. Cohen’s d effect sizes were calculated for normally distributed data only, as calculations for Cohen’s d are based on mean as the measure of central tendency, which does not appropriately reflect non-normal data distribution (indicated by– in the table). A negative score on the back-scratch test indicates a gap between fingers and on the sit-and-reach test indicates not reaching the toes. A positive score on the back-scratch test indicates overlapping fingers and, on the sit-and-reach test, indicates reaching past the toes. V̇O2PEAK = Peak oxygen uptake; METs = Metabolic equivalent of task; FACIT = Functional assessment of chronic illness therapy questionnaire; PSQI = Pittsburgh sleep quality index; SF-36 = 36-item short form questionnaire v1.0.