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Table 1 Comparison of characteristics and outcomes of patients in three groups

From: Feasibility and safety of laparoscopic radical cystectomy for male octogenarians with muscle-invasive bladder cancer

Parameter

A group

(age ≥ 80, LRC)

B group

(age < 80, LRC)

C group

(age ≥ 80, ORC)

H/χ2

P

Total number of patients

57

63

17

  

Age

84 (82–85)

66 (62–71)*

82 (81–82)

105.300

< 0.001

BMI (kg/m2)

23 (21–25)

25 (23–25)*

23 (20–24)

13.368

0.001

Previous abdominal operations

7.0% (4/57)

9.5% (6/63)

11.8% (2/17)

0.451

0.798

Hb (g/L)

110 (103–117)

112 (106–121)

107 (102–110)

8.548

0.014

Comorbid conditions

 Hypertension

71.9% (41/57)

60.3% (38/63)

88.2% (15/17)

5.344

0.069

 Coronary heart disease

57.9% (33/57)

49.2% (31/63)

52.9% (9/17)

0.908

0.635

 COPD

7.0% (4/57)

7.9% (5/63)

64.7% (11/17)*

39.106

< 0.001

 Diabetes

19.3% (11/57)

25.4% (16/63)

35.3% (6/17)

1.942

0.379

ASA score

   

4.803

0.091

 2

59.6% (34/57)

52.4% (33/63)

29.4% (5/17)

  

 3

40.4% (23/57)

47.6% (30/63)

70.6% (12/17)

  

Clinical stage

   

22.476

< 0.001

 T2NxM0

75.4% (43/57)

74.6% (47/63)

17.6% (3/17)*

  

 T3NxM0

24.6% (14/57)

25.4% (16/63)

82.4% (14/17)*

  

TURBT pathology

   

0.317

0.853

 G2

22.8% (13/57)

23.8% (15/63)

29.4% (5/17)

  

 G3

77.2% (44/57)

76.2% (48/63)

70.6% (12/17)

  

Operation time (min)

210 (195–215)

210 (200–220)

110 (100–120)*

45.594

< 0.001

Estimated blood loss (ml)

210 (195–230)

210 (210–230)

220 (210–600)*

7.370

0.025

Transfusion needed (n)

0

0

29.4% (5/17)*

18.937

< 0.001

Resected lymph node (n)

23 (21–26)

23 (20–26)

13 (12–15)*

43.669

< 0.001

Cystectomy pathology

   

25.988

< 0.001

 G3 pT2aN0

24.6% (14/57)

19.0% (12/63)

0*

  

 G3 pT2bN0

57.9% (33/57)

60.3% (38/63)

17.6% (3/17)*

  

 G3 pT3aN0

17.5% (10/57)

20.6% (13/63)

82.4% (14/17)*

  

Duration of pelvic drainage (day)

12 (10–14)

5 (5–5)*

16 (15–18)*

115.106

< 0.001

Hospital stay after surgery (day)

8 (8–9)

7 (7–7)*

14 (14–16)*

112.453

< 0.001

Adjuvant chemothera

0

15.9% (10/63)*

0

11.982

0.001

Follow-up duration (month)

64 (54–73)

66 (56–73)

45 (35–51)*

24.402

< 0.001

BC relapse

0

3.2% (2/63)

47.1% (8/17)*

27.778

< 0.001

Death

     

 BC

0

3.2% (2/63)

41.2% (7/17)*

23.320

< 0.001

 Other

5.2% (3/57)

3.2% (2/63)

29.4% (5/17)*

10.860

0.003

  1. Abbreviation: LRC Laproscopic radical cystectomy, ORC Open radical cystectomy, Hb Hemoglobin, BMI Body Mass Index, COPD Chronic obstructive pulmonary diseases, ASA American Society of Anesthesiologists, TURBT Transurethral bladder tumor resection, BC Bladder cancer
  2. *P < 0.05 vs. A group