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Table 2 Direct medical, non-medical and indirect costs in included studies

From: Subjective and objective financial toxicity among colorectal cancer patients: a systematic review

Author, Year

Country

Stage of Cancera

Year of Research

No. of patientsb

Direct medical cost

Direct non-medical

indirect cost

Perspective

Azzani et al. 2016 Azzani et al. 2017 [17, 18]

Malaysia

all stages

2013

138

RM 6544.5 (USD 2045.1) for stage I,

RM 7790.1 (USD 2434.4) for stage II,

RM 8799.1 (USD 2749.7) for stage III and

RM 8638.2 (USD 2699.4) for stage IV

NA

USD 452.2

Patient

O Céilleachair et al. 2017 [30]

Ireland

all stages

October 2007–September

2009

497

Average OOP: €1589 (USD 2192.8) among colorectal cancer survivors

€510(USD703.8)

NA

Patient

Seifeldin & Hantsch 1999 [23]

USA

all stages

1991–1994

The mean number of admissions: 237,754 per year

Total hospital charge is USD 4.5 billion per year (4 years period)

NA

NA

National HC

Huang et al. 2017 [25]

China

all stages

September 2012 to December 2014

2356

51,366 CNY (USD 8,284.8)

for stage I to 75,673 CNY (USD 12,205.3) for stage IV disease

5588 CNY(USD 901.2) per CRC patient

mean wage loss amounted to 6652 CNY (USD 1,072.9).

Patient and health insurance

Li et al. 2016 [26]

China

Not mentioned

January to December 2013

1211

USD 757,432.26

NA

NA

new

Rural Cooperative Medical Scheme (NCMS)

  1. aStage of Cancer: Unless indicated otherwise, stage of cancer indicates stage of colorectal cancer; bNo. of patients: number of patients; RM: Malaysian Ringgit; USD: United States Dollar; NA: not available; National HC: National health care; $: dollar sign; OOP: out-of-pocket; €: euro sign; USA: United States of America; CNY: Chinese yuan renminbi; CRC: colorectal cancer; NCMS: new rural cooperative medical scheme