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Table 4 Comparison of oncologic outcomes with Western studies

From: Amputation in patients with extremity soft tissue sarcoma: the experience of an East Asian referral center

  

Current study

Erstad et al.

Smith et al.

Stevenson et al.

Period

 

2000–2017

2001–2011

2004–2014

1996–2016

Number of cohort (amputated)

 

37

54

69

39

Published

 

2023 

2018

2018

2017

Amputation number and rate for localized STS

3.4% (22/596)

(n = 54)

(n = 59)

(n = 39)

Amputation number and rate for primary localized STS

1.8% (9/490)

(n = 18)

4.1% (23/556)

(n = 16)

Localized STS

DSS

89.9%

NA

49.8%(3 year)

NA

LRFS

84.1%

NA

89.6%(3 year)

NA

MFS

84.6%

NA

44.0%(3 year)

NA

Primary localized STS

DSS

85.7%

68%

30.5%(OS, 3 year)

52.2%(10 year)

LRFS

87.5%

75%

72.9%(3 year)

90.0%(10 year)

MFS

87.5%

53%

33.4%(3 year)

31.0%(10 year)

Recurrent localized STS

DSS

92.3%

33%

62.8%(OS, 3 year)

44.1%(10 year)

LRFS

81.8%

85%

97.0%(3 year)

83.7%(10 year)

MFS

82.1%

23%

57.2%(3 year)

42.2%(10 year)

Indications in primary localized STS*

a(22%), b(78%)

a(39%), b(61%)

b(13%)

b(50%), c(50%)

Indication and timing in recurrent localized STS*

a(23%), b(92%)

a(36%), b(41%)

b(16%)

a(17.4%), b(52.2%)

  1. STS: soft tissue sarcoma, DSS: disease specific survival, LRFS: local recurrence free survival, MFS: metastasis free survival, NA: not available
  2. *Regarding indications, alphabetics imply the followings; aSignificant impairment or loss of limb function due to tumor, bNo technical salvage options = extensive involvement and involvement of critical structure, cInoperable due to huge size