FERMT1 promotes cell migration and invasion in non-small cell lung cancer via regulating PKP3-mediated activation of p38 MAPK signaling

Liu, Bao; Feng, Yan; Xie, Naiying; Yang, Yang; Yang, Dameng

doi:10.1186/s12885-023-11812-3

Fig. 5

From: FERMT1 promotes cell migration and invasion in non-small cell lung cancer via regulating PKP3-mediated activation of p38 MAPK signaling

FERMT1 regulates MAPK signaling pathway in NSCLC cells. (A) In the TCGA database, GSEA analysis revealed a positive correlation between FERMT1 expression and the MAPK signaling pathway. (B) To ascertain the protein levels of FERMT1, p38, and p-p38 in FERMT1 overexpression or knockdown cells, Western blotting was employed. (C– F) Quantification of the protein levels of FERMT1 (C), p38 (D), p-p38 (E) and p-p38/p38 (F) in (B). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Fig. 5

BMC Cancer

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