Fig. 3
From: Co-expression of IL-21-Enhanced NKG2D CAR-NK cell therapy for lung cancer
Estimation of cytotoxic activity in CAR-NK-92 cells. (A) Line plots showing the cytotoxicity of NK-92, NKG2D CAR-NK-92 cells, and NKG2D-IL-21 CAR-NK-92 cells against the lung cancer cell lines at a different effector to target (E: T) ratios for 4 h. The expression level of CD107a (B) and the released amount of IFN-γ (C) in CAR-NK-92 cells were measured after co-culturing with lung cancer cell lines at a 5:1 ratio for 4 h by flow cytometry. Data were representative of three independent experiments. ** P < 0.01; ns, not significant