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Fig. 4 | BMC Cancer

Fig. 4

From: Identification of CD8+ T-cell exhaustion signatures for prognosis in HBV-related hepatocellular carcinoma patients by integrated analysis of single-cell and bulk RNA-sequencing

Fig. 4

Construction of the TEI of CD8+T cell exhaustion-related genes (TERGs). A The volcano diagram depicting the differential expression of genes between HBV-negative and HBV-positive HCC samples. B 20 TERGs that exhibit differential expression between HBV-positive and HBV-negative HCC patients, and have the potential to impact the prognosis of HCC. C Univariate Cox analysis of OS in HCC. D Selection of the optimal parameter (lambda) in the LASSO model. E LASSO coefficients of the 20 TERGs in TCGA cohort

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