Fig. 1

UTP11 expression was higher in HCC samples compared to normal tissues. (A) UTP11 expression levels in 33 tumor tissues compared to normal tissues from the TCGA database generated by TIMER2.0 database (http://timer.comp-genomics.org/) [44]. The expression of UTP11 was represented using box plots. (B) The expression levels of UTP11 in HCC and normal paracancerous tissues from TCGA database. (C) UTP11 was highly expressed in tumor tissues than in normal tissues in 50 pairs of HCC paired samples from TCGA database. (D) The ROC curve analysis of UTP11 was performed in predicting tumor versus normal outcome. The horizontal coordinate is the False Positive Rate (FPR) and the vertical coordinate is the True Positive Rate (TPR). (E) The protein expression levels of UTP11 in paracancerous and HCC tissues were detected by IHC method which was generated by HPA database. * P < 0.05; ** P < 0.01; *** P < 0.001