Table 2 Nabiximols/placebo titration regimen
Day | Number of Sprays | ||
|---|---|---|---|
Morning Between waking-up and 12pm | Afternoon Between 4pm and bedtime | Total number of sprays per day | |
1 | 0 | 1 | 1 |
2 | 0 | 1 | 1 |
3 | 0 | 2 | 2 |
4 | 0 | 2 | 2 |
5 | 1 | 2 | 3 |
6 | 1 | 3 | 4 |
7 | 1 | 4 | 5 |
8 | 2 | 4 | 6 |
9 | 2 | 5 | 7 |
10 | 3 | 5 | 8 |
11 | 3 | 6 | 9 |
12 | 4 | 6 | 10 |
13 | 4 | 7 | 11 |
14 | 5 | 7 | 12 |