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Table 4 Univariate Survival analysis for overall survival (Univariate Cox regression; shown are the Hazard ratio, the 95% confidence interval and the p-value. P-values < 0.05 were regarded as significant)

From: Preoperative IL-8 levels as prognostic indicators of overall survival: an extended follow-up in a prospective cohort with colorectal liver metastases

Univariate Cox Regression analysis for Overall Survival

 

Hazard

95% CI interval

p-Value

Leuk

0.9

0.42—1.19

0.76

NLR

2.61

1.12—6.08

0.03

TLR

1.17

0.53—2.58

0.7

CRP

1.69

0.77—3.69

0.19

IL6

2.13

0.97—4.68

0.06

IL8

2.23

1.03—4.83

0.04

Bilirubin

1.44

0.68—3.06

0.35

Quick

0.71

0.34—1.49

0.36

Sex

0.6

0.26—1.37

0.23

Synchronous metastasis

2.5

0.93—6.71

0.07

N pos

1.86

0.84—4.14

0.13

T stage ≥ 3

1.94

0.72—5.19

0.19

G3

1.75

0.56—5.43

0.34

ASA ≥ 3

1.43

0.65—3.14

0.37

Diabetes

0.38

0.07—2.19

0.28

neoadj. CTX

1.02

0.76—1.38

0.89

No previous liver resections

0.57

0.27—1.21

0.14

3 or more Metastases

1.92

0.84—4.36

0.12

other Metastases

2.42

1.13—5.19

0.02

largest Liver-Metastasis >  = 4 cm

1.25

0.56—2.77

0.59

CEA > 60

0.95

0.36—2.56

0.93

R0

1.04

0.31—3.18

0.94

Age > 70

1.15

0.54—2.46

0.72

BMI larger 30

0.69

0.21—2.29

0.54

Major liver resection

0.6

0.24—1.48

0.27

  1. NL = Neutrophil Lymphocyte Ratio; TL = Thrombocyte Lymphocyte ratio
  2. CRP C-reactive Protein, IL-6 Interleukin 6, IL-8 Interleukin 8, CEA