From: Efficacy and indications of gamma knife radiosurgery for recurrent low-and high-grade glioma
Patient characteristics | Number of patients (%) | Patient characteristics | Number of patients (%) |
---|---|---|---|
Sex | Â | KPS | Â |
Female | 58(54.2) | ≥80 | 48(44.9) |
Male | 49(65.8) | <80 | 59(55.1) |
Pathological grade | Â | Number of targets | Â |
LGG | 39(36.4) | Single | 45(42.1) |
HGG | 68(63.6) | Multiple | 62(57.9) |
Adjuvant treatment after initial surgery | Â | Total volume of targets | Â |
 | ≥18.5 cm3 | 51(47.7) | |
Chemoradiotherapy | 51(47.7) | <18.5 cm3 | 49(52.3) |
EBRT only | 25(23.4) | Maximum dose | Â |
TMZ only | 5(4.7) | ≥24.5 Gy | 54(50.5) |
GKRS only | 10(9.3) | <24.5Â Gy | 53(49.5) |
None | 16(15.0) | Marginal dose | Â |
Age at GKRS procedure |  | ≥12.5 Gy | 54(50.5) |
≥50 years | 58 (54.2) | <12.5 Gy | 53(49.5) |
<50 years | 49(45.8) | Two and more GKRS | Â |
Recurrence time interval | Â | Yes | 36(33.6) |
≥15 months | 54(50.5) | No | 71(66.4) |
<15 months | 53(49.5) | Bevacizumab used after recurrence | Â |
Surgery for recurrence | Â | Yes | 14(13.1) |
Yes | 27(25.2) | No | 93(86.9) |
No | 80(74.8) | Â | Â |