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Table 1 Baseline clinical characteristics of all Patients pre- or post-GKRS [%]

From: Efficacy and indications of gamma knife radiosurgery for recurrent low-and high-grade glioma

Patient characteristics

Number of patients (%)

Patient characteristics

Number of patients (%)

Sex

 

KPS

 

Female

58(54.2)

≥80

48(44.9)

Male

49(65.8)

<80

59(55.1)

Pathological grade

 

Number of targets

 

LGG

39(36.4)

Single

45(42.1)

HGG

68(63.6)

Multiple

62(57.9)

Adjuvant treatment after initial surgery

 

Total volume of targets

 
 

≥18.5 cm3

51(47.7)

Chemoradiotherapy

51(47.7)

<18.5 cm3

49(52.3)

EBRT only

25(23.4)

Maximum dose

 

TMZ only

5(4.7)

≥24.5 Gy

54(50.5)

GKRS only

10(9.3)

<24.5 Gy

53(49.5)

None

16(15.0)

Marginal dose

 

Age at GKRS procedure

 

≥12.5 Gy

54(50.5)

≥50 years

58 (54.2)

<12.5 Gy

53(49.5)

<50 years

49(45.8)

Two and more GKRS

 

Recurrence time interval

 

Yes

36(33.6)

≥15 months

54(50.5)

No

71(66.4)

<15 months

53(49.5)

Bevacizumab used after recurrence

 

Surgery for recurrence

 

Yes

14(13.1)

Yes

27(25.2)

No

93(86.9)

No

80(74.8)

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