Table 3 Meta-analysis results for the association of NBAT-1 with clinicopathological parameters
Clinicopathological parameters | Studies(n) | Numbers of patients | RR (95% CI) | P value | Heterogeneity | ||
|---|---|---|---|---|---|---|---|
I2 | Ph | Model | |||||
Age (elderly vs. nonelderly) | 8 | 651 | 1.01(0.87,1.17) | 0.93 | 30.00% | 0.19 | Fixed effects |
Gender (male vs. female) | 8 | 674 | 0.95(0.83,1.08) | 0.40 | 0.00% | 0.99 | Fixed effects |
TNM stage (III/IV vs. I/II) | 4 | 912 | 0.66(0.55,0.79) | 0.00 | 0.00% | 0.75 | Fixed effects |
Lymph node metastasis (+ vs. -) | 8 | 1303 | 0.62(0.46,0.84) | 0.00 | 60.10% | 0.01 | Random effects |
Tumour depth invasion(T3/4 vs. T1/T2) | 3 | 890 | 0.62(0.49,0.80) | 0.00 | 50.90% | 0.13 | Fixed effects |
Distant Metastasis(+ vs. -) | 3 | 806 | 0.50 (0.33,0.76) | 0.00 | 36.40% | 0.21 | Fixed effects |
Histological grade(poor/others vs. well/moderate) | 5 | 443 | 0.68(0.57,0.81) | 0.00 | 39.00% | 0.16 | Fixed effects |
Tumour size | 9 | 731 | 0.72(0.55,0.93) | 0.01 | 55.70% | 0.02 | Random effects |