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Fig. 1 | BMC Cancer

Fig. 1

From: Expression and prognostic value of APOBEC2 in gastric adenocarcinoma and its association with tumor-infiltrating immune cells

Fig. 1

APOBEC2 genetic alteration, transcripts, and protein expression pattern in STAD and adjacent tissues. (a) APOBEC2 genetic alteration (mutation, amplification, deep deletion and multiple alteration) in 777 STAD. Data were obtained from cBioPortal and shown by composition ratio. (b) APOBEC2 genetic amplification in 89 Asians STAD. Data were obtained from cBioPortal and shown by composition ratio. (c) Box plots of comparing detail APOBEC2 transcripts between normal and STAD. Data were obtained from GEPIA and the method for differential analysis is one-way ANOVA. (d) Comparison of IHC score of 48 paired malignant and non-malignant specimens. (e) Comparison of IHC score of 39 fundic gland mucosa tissues, 48 cancer tissues and 9 pyloric gland mucosa tissues. (f) Comparison of IHC score of 39 fundic gland mucosa tissues, 496 cancer tissues and 9 pyloric gland mucosa tissues. Paired t-test was used in Fig. 1d. The Kruskal–Wallis test was used in Fig. 1e and f. *P < 0.05, ****P < 0.0001, ns (no significant)

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