Correlation between preoperative peripheral blood NLR, PLR, LMR and prognosis of patients with head and neck squamous cell carcinoma

Table 3 Comparison of overall survival for 304 HNSCC patients

Variables	Univariate analysis			Multivariate analysis
Variables	HR	95%CI	P value	HR	95%CI	P value
Gender(male/female)	1.442	0.708–2.940	0.313
Age (< 63 ± 10.56/≥63 ± 10.56 years)	1.019	0.993–1.045	0.156
Smoking(yes/no)	1.403	0.795–2.474	0.243
Drinking(yes/no)	1.284	0.759–2.173	0.351
Tumor location (oral/oropharynx/larynx/hypopharynx/else)			0.067
WBC(< 7.96/≥7.96 × 10^9/L)	1.128	1.012–1.258	0.030*	0.914	0.800-1.044	0.185
NEU(< 4.57/≥4.57 × 10^9/L)	1.300	1.199–1.411	0.001*	1.234	1.107–1.375	0.000*
MON(< 0.48/≥0.48 × 10^9/L)	2.220	0.816–6.039	0.118
LYM(< 2.44/≥2.44 × 10^9/L)	0.684	0.462–1.014	0.059
PLT(< 246.5/≥246.5/L)	1.004	1.001–1.007	0.007*	1.002	0.998–1.005	0.327
NLR(< 1.94/≥1.94)	1.176	1.120–1.235	0.001*	1.104	1.016-1.200	0.019*
PLR(< 107.8/≥107.8)	1.002	1.000-1.005	0.073
LMR(< 5.08/≥5.08)	0.930	0.815–1.062	0.285
pN stage(N₀/N_1 − 3)	0.622	0.479–0.807	0.001*	1.097	0.799–1.508	0.567
TNM stage(I-II/III-IV)	0.474	0.351–0.642	0.001*	0.540	0.375–0.778	0.001*
Postoperative complication(yes/no)	0.607	0.460–0.799	0.001*	0.713	0.536–0.948	0.020*

Comparison of OS for HNSCC patients based on univariate and multivariate analysis in NLR, PLR and LMR. HR hazard ratio, CI confidence interval
*Statistically significant p < 0.05

ISSN: 1471-2407