Table 3 Univariable analysis of ultrasound and clinicopathological features of primary tumor in the training cohort

Age

 < 60

121(64.7%)

34(60.7%)

Reference

 ≥ 60

66(35.3%)

22(39.3%)

1.186

0.642–2.193

0.586

Location

 UIQ

31(16.6%)

8(14.3%)

Reference

 LIQ

13(7.0%)

3(5.4%)

0.812

0.341–1.934

0.638

 LOQ

36(19.3%)

11(19.6%)

0.726

0.195–2.701

0.633

 UOQ

107(57.2%)

34(60.7%)

0.962

0.442–2.093

0.921

Orientation

 Parallel

137(73.3%)

37(66.1%)

Reference

 Non-parallel

50(26.7%)

19(33.9%)

1.407

0.741–2.671

0.296

Shape

 Regular

19(10.2%)

8(14.3%)

Reference

 Irregular

168(89.8%)

48(85.7%)

0.679

0.280–1.646

0.391

Margin

 Circumscribed

35(18.7%)

6(10.7%)

Reference

 Non-circumscribed

152(81.3%)

50(89.3%)

1.919

0.762–4.830

0.166

Calcification

 No

83(44.4%)

21(37.5%)

Reference

 Yes

104(55.6%)

35(62.5%)

1.330

0.720–2.456

0.362

Attenuation

 No

128(68.4%)

31(55.4%)

Reference

 Yes

59(31.6%)

25(44.6%)

1.750

0.950–3.222

0.073

ER

 Negative

69(36.9%)

20(35.7%)

Reference

 1 + 

23(12.3%)

8(14.3%)

0.870

0.438–1.727

0.690

 2 + 

26(13.9%)

5(8.9%)

1.043

0.411–2.652

0.929

 3 + 

69(36.9%)

23(41.1%)

0.577

0.198–1.677

0.312

PR

 Negative

81(43.3%)

28(50.0%)

Reference

 1 + 

30(16.0%)

10(17.9%)

1.267

0.587–2.736

0.546

 2 + 

32(17.1%)

6(10.7%)

1.222

0.468–3.189

0.682

 3 + 

44(23.5%)

12(21.4%)

0.688

0.233–2.026

0.497

Her-2

 Negative

150(80.2%)

45(80.4%)

Reference

 Positive

37(19.8%)

11(19.6%)

0.991

0.468–2.100

0.981

P53

 Negative

81(43.3%)

28(50.0%)

Reference

 Positive

87(46.5%)

26(46.4%)

0.352

0.077–1.613

0.179

 Unknow

19(10.2%)

2(3.6%)

1.157

0.626–2.137

0.642

Ki-67

  < 14

31(16.6%)

3(5.4%)

Reference

  ≥ 14

151(80.7%)

53(94.6%)

0.276

0.081–0.939

0.039*

 Unknow

5(2.7%)

0(0.0%)

Tumor size

 T1

102(54.5%)

17(30.4%)

Reference

 T2

85(45.5%)

39(69.6%)

2.753

1.454–5.212

0.002*

Histological grade

 I

16(8.6%)

2(3.6%)

Reference

 II

84(44.9%)

33(58.9%)

3.143

0.685–14.429

0.141

 III

83(44.4%)

21(37.5%)

2.024

0.431–9.498

0.371

Unknow

4(2.1%)

0(0.0%)