Table 1 Traditional IHC vs. 3D approach
| Â | Traditional IHC | 3D approach |
|---|---|---|
Processing cost | 3D approach costs 10 times more than IHC per case | Â |
Capital equipment cost | The cost is nearly similar in IHC and 3D approach | Â |
Structural/Molecular information | 3D approach provides 45 times more information than a single-section IHC | Â |
Processing time | 3 working days | 7 working days |
Histological information | Fragmentary | Continuous |
Image pre-process | Required | Not required |
Diagnostic stratification | Less accurate | More accurate |
Utilization for downstream assays | Not applicable since destructive | Applicable since non-destructive |