Adverse events | WBRT + SIB (n = 82) | WBRT (n = 83) | ||
---|---|---|---|---|
Grade 1 or 2, n (%) | Grade 3, n (%) | Grade 1 or 2, n (%) | Grade 3, n (%) | |
Fatigue | 11(13) | 0(0) | 9(11) | 0(0) |
Headache | 21(26) | 0(0) | 20(24) | 2(2) |
Dizziness | 13(16) | 1(1) | 21(25) | 1(1) |
Nausea | 11(13) | 0(0) | 16(19) | 0(0) |
Vomiting | 5(6) | 0(0) | 9(11) | 0(0) |
Fever | 2(2) | 0(0) | 1(1) | 0(0) |
Leukopenia | 8(10) | 0(0) | 5(6) | 2(2) |
Thrombocytopenia | 0(0) | 0(0) | 2(2) | 0(0) |
Epilepsy | 3(4) | 0(0) | 1(1) | 0(0) |
Radiation dermatitis | 1(1) | 0(0) | 0(0) | 0(0) |
Consciousness disorder | 0(0) | 0(0) | 1(1) | 0(0) |
Cephalic and facial edema | 0(0) | 0(0) | 1(1) | 0(0) |
Supraventricular tachycardia | 0(0) | 0(0) | 1(1) | 0(0) |
Hypokalemia | 0(0) | 0(0) | 1(1) | 0(0) |
Radiation-induced brain injury | 7(9) | 1(1) | 2(2) | 0(0) |