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Table 2 Adverse events

From: Adding simultaneous integrated boost to whole brain radiation therapy improved intracranial tumour control and minimize radiation-induced brain injury risk for the treatment of brain metastases

Adverse events

WBRT + SIB (n = 82)

WBRT (n = 83)

Grade

1 or 2, n (%)

Grade 3, n (%)

Grade 1 or 2, n (%)

Grade 3, n (%)

Fatigue

11(13)

0(0)

9(11)

0(0)

Headache

21(26)

0(0)

20(24)

2(2)

Dizziness

13(16)

1(1)

21(25)

1(1)

Nausea

11(13)

0(0)

16(19)

0(0)

Vomiting

5(6)

0(0)

9(11)

0(0)

Fever

2(2)

0(0)

1(1)

0(0)

Leukopenia

8(10)

0(0)

5(6)

2(2)

Thrombocytopenia

0(0)

0(0)

2(2)

0(0)

Epilepsy

3(4)

0(0)

1(1)

0(0)

Radiation dermatitis

1(1)

0(0)

0(0)

0(0)

Consciousness disorder

0(0)

0(0)

1(1)

0(0)

Cephalic and facial edema

0(0)

0(0)

1(1)

0(0)

Supraventricular tachycardia

0(0)

0(0)

1(1)

0(0)

Hypokalemia

0(0)

0(0)

1(1)

0(0)

Radiation-induced brain injury

7(9)

1(1)

2(2)

0(0)

  1. Abbreviations: WBRT whole-brain radiation therapy, SIB simultaneous integrated boost