Fig. 8

Single-channel neighborhood cell analysis. A Schematic diagram of “cancer nest”. B Representative schematic of “cancer nest”. C Schematic diagram of cell number analysis within the 100 μm range. D Representative schematic of nearest distance analysis. E Comparison of the number of CD8 + cells in the 100um range of panCK-positive cells. F Comparison of the number of PD-L1 + cells in the 100um range of panCK-positive cells. G Comparison of the number of CD8 + cells in the 100um range of PD-L1-positive cells. H Analysis of the average closest distance between panCK + cells and CD8 + cells. I Analysis of the average closest distance between panCK + cells and PD-L1 + cells. J Analysis of the average closest distance between PD-L1 + cells and CD8 + cells