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Fig. 6 | BMC Cancer

Fig. 6

From: CD147 promotes breast cancer migration and invasion by inducing epithelial-mesenchymal transition via the MAPK/ERK signaling pathway

Fig. 6

The expression of pERK and tERK in BT549 and MCF-7 cells. (A) Western blot analysis of MEK, p-MEK, ERK, and p-ERK protein levels in BT549 cell groups, indicating increased p-MEK and p-ERK in BT549-liposome-CD147. (B) Ratios of p-MEK/MEK and p-ERK/ERK significantly increase in BT549-liposome-CD147. (C) Western blot displays reduced p-MEK and p-ERK levels in MCF-7-liposome-si-CD147. (D) Decreased p-MEK/MEK and p-ERK/ERK ratios in MCF-7-liposome-si-CD147 indicate MAPK/ERK pathway modulation. **P < 0.01, vs. BT549/MCF-7; ##P < 0.01, vs. BT549-liposome/MCF-7-liposome; &&P < 0.01, vs. BT549-liposome-CD147/MCF-7-liposome-siNC

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BMC Cancer

ISSN: 1471-2407

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