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Fig. 4 | BMC Cancer

Fig. 4

From: CD147 promotes breast cancer migration and invasion by inducing epithelial-mesenchymal transition via the MAPK/ERK signaling pathway

Fig. 4

Effects of CD147 on 5-FU resistance in breast cancer cells. (A) CCK-8 assay indicates increased cell viability in BT549-liposome-CD147 at higher 5-FU concentrations. (B) CCK-8 assay demonstrates reduced cell viability in MCF-7-liposome-si-CD147 at higher 5-FU concentrations. (C) Increased IC50 value in BT549-liposome-CD147 cells. (D) Reduced IC50 value in MCF-7-liposome-si-CD147. **P < 0.01, vs. BT549/MCF-7; ##P < 0.01, vs. BT549-liposome/MCF-7-liposome; &&P < 0.01, vs. BT549-liposome-CD147/MCF-7-liposome-siNC.

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BMC Cancer

ISSN: 1471-2407

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