Table 2 Classification of cited references

[1]

Molecular Basis of Cardiac Myxomas

Histopathology, Clinical Details

Focuses on cardiac myxoma (CM), the most prevalent benign cardiac tumors.

[2]

Cardiac Organoids

Human Samples

Addresses the limited regenerative capacity of the adult human heart, a key consideration in cardiac diseases.

[3]

Cardiac Regeneration

Histopathology

Explores cardiac regeneration, which is directly related to the study’s focus on the limited regenerative potential of cardiomyocytes in cardiac myxoma (CM) development

[4]

Cardiomyogenesis

Histopathology

Examines cardiomyogenesis, providing insights into the differentiation processes of cardiomyocytes that are crucial for understanding cardiac myxoma (CM) development.

[5]

Cardiac regeneration and repair

Histopathology

Investigates cardiac regeneration and repair, which is relevant to the study as it delves into the regenerative potential of cardiac cells, a key aspect in understanding cardiac myxoma (CM) and its implications for cardiomyocyte biology.

[6]

Cardiomyocyte cell-cycle arrest

Histopathology

Explores cardiomyocyte cell-cycle arrest, a critical concept to grasp the limited regenerative potential of cardiomyocytes

[19]

Primary Cardiac Tumors

Clinical Details

Provides insights into primary cardiac tumors, which is relevant to understanding the rarity of benign cardiac myxoma (CM) and their unique features.

[7]

Heart regeneration

Histopathology

Discusses the challenges related to heart regeneration and the limited regenerative capacity of cardiomyocytes, which is crucial for understanding the significance of cardiac myxoma (CM).

[8]

Cardiac Stem Cells

Histopathology

Explores the relevance of cardiac stem cells, which play a role in understanding cardiac regeneration and potential connections to the cardiac myxoma (CM) development

[9]

Cardiac transcription factors

Histopathology

Investigates cardiac transcription factors, shedding light on how they may influence cardiomyocyte biology and their resistance to neoplastic transformations, possibly contributing to the benign nature of cardiac myxoma (CM)

[16]

Cardiac transcription factors

Human Samples

Investigates the implications of cardiac transcription factors, shedding light on cardiac myxoma (CM) development and its relationship with cardiomyocyte biology

[10]

Cardiac Development and Remodeling

Histopathology

Explores cardiac development and remodeling, potentially offering insights into cardiac myxoma (CM) development and its implications for cardiac regeneration

[17]

Cardiac Organoids

Human Samples

Investigates cardiac organoids, providing valuable information on cardiac biology, which can aid in understanding cardiac myxoma (CM) development and its relevance to cardiac regeneration.

[18]

Cardiac Organoids

Human Samples

This provides valuable insights in unlocking the nature of cardiomyocytes

[11]

Cardiac Organoids

Human Samples

This provides valuable insights in unlocking the nature of cardiomyocytes

[12]

Cardiac Organoids

Human Samples

This provides valuable insights in unlocking the nature of cardiomyocytes

[13]

Cardiac stem cells

Human Samples

Focuses on cardiac stem cells, which are of interest due to their potential role in understanding cardiac myxoma (CM) and cardiac regeneration.

[14]

Cardiac Tumors

Clinical Details

Addresses the topic of cardiac tumors, which is relevant for understanding the etiology and characteristics of cardiac myxoma (CM)

[15]

Cardiac Tumors

Clinical Details

Explores cardiac tumorigenesis

[20]

Heart Regeneration

Human Samples

Provides insights into heart regeneration, a relevant concept for studying the limited regenerative potential of cardiomyocytes.

[21]

Cardiac Regeneration

Human Samples

Explores cardiac regenerative potential

[22]

Cardiac Regenerative Pathways

Human Samples

Essential to investigate the nature of cardiomyocytes

[23]

Cardiac Organoids

Human Samples

Provides step by step progression of the cardiac development

[24]

Cardiac Organoids

Human Samples

Provides insights into the cardiac developmental processes

[152]

Cardiac Reprogramming Factors

Histopathology

Addresses the genetic architecture involved in cardiac reprogramming

[153]

Cardiogenesis

Human Samples

Provides valuable details about the process of cardiac development

[154]

Cardiac Progenitors

Histopathology

Addresses the development of cardiomyocytes from cardiac progenitors

[155]

Heart Field

Human Samples

Provides valuable details about early stages of cardiac development

[156]

Heart Field

Histopathology

Provides valuable details about early stages of cardiac development

[58]

Heart Field

Histopathology

Provides valuable details about early stages of cardiac development

[157]

Cardiac Progenitor Cells

Human Samples

Addresses the development of cardiomyocytes from cardiac progenitors

[158]

Regenerative Cardiology

Human Samples

Helps to explore the relationship between cardiac myxoma (CM) and the limited regenerative potential of cardiomyocytes

[159]

Cardiac development and remodeling

Human Samples

Essential in understanding the mechanisms governing cardiac cell fate

[30]

Cardiogenesis

Human Samples

Essential to analyze the intricate processes of cardiac development

[25]

Islet1 - control of cardiomyocyte cell fate

Histopathology

Provides insights into Isl1 and its role in controlling cardiomyocyte cell fate, which is a key aspect of the study’s focus on cardiac myxomas and the transformation of cardiomyocytes into progenitor-like cells

[26]

Islet1 - cardiac progenitor proliferation

Histopathology

Offers insights into Isl1 and its role in cardiac progenitor proliferation

[27]

Islet1 - Cardiac Progenitor Cells

Human Samples

Focuses on Isl1 as one of the earliest expressed transcription factors in Cardiac Progenitor Cells

[28]

Islet1 - Cardiomyogenesis

Histopathology

Discusses Isl1 and its role in cardiomyogenesis, contributing to the understanding of cardiac development

[29]

Islet1 - Cardiac Development

Human Samples

Provides insights into Isl1 and its role in controlling cardiomyocyte cell fate

[31]

Islet1 and Tbx5 interaction

Human Samples

Provides insights into how these interactions may influence cardiac programming

[32]

Islet1 in Cardiac Progenitors

Human Samples

Points to the significance of Isl1 in cardiac progenitor cells

[33]

Cardiac Stem Cells

Histopathology

Aligns with the study’s exploration of cardiac myxomas and their potential influence on the limited regenerative capacity of cardiomyocytes

[34]

Islet1 – Cardiac Differentiation

Histopathology

Provides insights into the influence of Isl1 on the process of cardiac differentiation

[35]

Islet1 – Cardiac Repair

Histopathology

Provides insights into the influence of Isl1 on the process of cardiac repair

[36]

Islet1 and Nkx2–5 interaction

Histopathology

Provides insights about how these interactions may influence cardiac programming

[37]

Islet1 with Mef2c and GATA4

Histopathology

Provides insights about how these interactions may influence cardiac programming

[38]

Islet1 with Nkx2–5 and GATA4

Histopathology

Provides insights about how these interactions may influence cardiac programming

[39]

Islet1 - Cardiac Morphogenesis

Histopathology

Offers insights into the factors influencing cardiac genetic architecture

[160]

Islet1 in Cancer Progression

Human Samples

Essential to understand the nature and impact of Isl1 in tumorigenesis

[161]

Islet1 in different tumors

Human Samples

Essential to understand the nature and impact of Isl1 in tumorigenesis

[162]

Islet1 in different tumors

Human Samples

Essential to understand the nature and impact of Isl1 in tumorigenesis

[163]

Islet1 in tumorigenesis

Human Samples

Essential to understand the nature and impact of Isl1 in tumorigenesis

[164]

Islet1 in different tumors

Histopathology

Essential to understand the nature and impact of Isl1 in tumorigenesis

[40]

Multipotent cardiac stem cells

Human Samples

Essential to explore the aspects of cardiac regeneration and differentiation

[41]

Nkx2–5 and Isl1 interaction

Histopathology

Provides insights about how these interactions may influence cardiac programming

[42]

Isl1 repression

Histopathology

Related to the study’s interest in the control of cardiomyocyte cell fate and differentiation.

[43]

Islet-1 modulating estrogen receptor

Histopathology

Provides insights about how these interactions may influence cardiac programming

[44]

Islet-1 modulating estrogen receptor

Histopathology

Provides insights about how these interactions may influence cardiac programming

[45]

Islet1 and GATA4 interaction

Histopathology

Provides insights about how these interactions may influence cardiac programming

[46]

Brg1/Baf60 – Smarcd3 complex in Pluripotency and Differentiation

Histopathology

Relevant to understanding the molecular mechanisms related to cardiomyocyte reprogramming in cardiac myxoma (CM)

[47]

Brg1/Baf60 – Smarcd3 complex in Cardiac Development

Human Samples

Provides insights into the regulatory pathways that may be involved in cardiac myxoma (CM) development

[48]

Brg1/Baf60 – Smarcd3 complex in Development and Cancers

Human Samples

Potentially offering valuable information about how it may play role in the transformation of cardiomyocytes into progenitor-like cells in cardiac myxoma (CM) development

[49]

Brg1/Baf60 – Smarcd3 complex in EMT transition

Human Samples

Essential to investigate the progenitor-like state in cardiac myxoma (CM)

[50]

Brg1/Baf60 – Smarcd3 complex in EMT transition

Human Samples

Essential to investigate the progenitor-like state in cardiac myxoma (CM)

[51]

Brg1/Baf60 – Smarcd3 complex and p53 interaction

Histopathology

Addresses how key genes are regulated in cardiac development

[52]

Brg1/Baf60 – Smarcd3 complex in cardiomyocyte fate

Histopathology

Provides insights into the development of cardiogenic cell fate

[53]

Brg1/Baf60 – Smarcd3 complex in cardiac progenitor cells

Histopathology

Relevant to understanding how these cells may influence the development of cardiac myxoma and the reversion of cardiomyocytes to a progenitor-like state

[54]

Brg1/Baf60 – Smarcd3 complex in cardiogenesis

Histopathology

Provides insights into the regulatory pathways that may be involved in cardiac myxoma (CM) development

[55]

Brg1/Baf60 – Smarcd3 complex: Tbx5 in cardiogenesis

Histopathology

Provides insights about how these interactions may influence cardiac programming

[165]

Brg1/Baf60 – Smarcd3 complex in development processes

Histopathology

Provides insights about the nature of this complex

[166]

Brg1/Baf60 – Smarcd3 complex in tumorigenesis

Histopathology

Essential to understand the nature and impact of Baf60 in tumorigenesis

[56]

Brg1/Baf60 – Smarcd3 complex’s interaction with Nkx2–5

Human Samples

Provides insights about how these interactions may influence cardiac programming

[57]

Brg1/Baf60 – Smarcd3 complex’s interaction with Nkx2–5

Histopathology

Provides insights about how these interactions may influence cardiac programming

[58]

Nkx2–5 in heart field

Histopathology

Provide insights into the potential role of Nkx2–5 in cardiac myxoma development and its control over cardiac progenitor cells.

[167]

Nkx2–5 in controlling proliferation

Histopathology

Relevant to elucidate Nkx2–5’s potential role in limiting tumorigenesis in cardiac myxomas by controlling the proliferation of cardiac progenitor cells

[59]

Nkx2–5 and its interaction with wnt pathway

Histopathology

Provides insights about how these interactions may influence cardiac programming

[60]

Nkx2–5 and wnt in cardiogenesis

Histopathology

Provides insights about how these interactions may influence cardiac programming

[61]

Nkx2–5 as tumor suppressor

Histopathology

Provides insights into how Nkx2–5 exerts influence over the risk of cardiac tumorigenesis

[62]

Nkx2–5 in cardiogenesis

Histopathology

Potentially shedding light on its influence in cardiac myxoma development

[63]

Nkx2–5 and its interactions with Tbx1 in cardiogenesis

Histopathology

Provides insights about how these interactions may influence cardiac programming

[64]

Interaction of Nkx2–5 with tumor suppressor genes

Human Samples

Provides insights about how these interactions may influence cardiac programming

[65]

Nkx2–5 in cardiac differentiation

Histopathology

Provides insights into how Nkx2–5 exerts influence over the risk of cardiac tumorigenesis

[66]

Nkx2–5 and its interaction with BMP signaling

Histopathology

Provides insights about how these interactions may influence cardiac programming

[67]

Nkx2–5 and its interaction with FGF

Histopathology

Provides insights about how these interactions may influence cardiac programming

[68]

Nkx2–5 and its interactions with cardiac regulator genes

Histopathology

Provides insights about how these interactions may influence cardiac programming

[168]

Nkx2–5 in tumors

Human Samples

Essential to understand the nature and impact of Nkx2–5 in tumorigenesis

[169]

Nkx2–5 in tumors

Human Samples

Essential to understand the nature and impact of Nkx2–5 in tumorigenesis

[170]

Nkx2–5 and its interaction with tumor suppressor gene

Histopathology

Provides insights about how these interactions may influence cardiac programming

[171]

Nkx2–5 in tumors

Human Samples

Essential to understand the nature and impact of Nkx2–5 in tumorigenesis

[172]

Nkx2–5 in tumors

Human Samples

Essential to understand the nature and impact of Nkx2–5 in tumorigenesis

[173]

Nkx2–5 in tumors

Human Samples

Essential to understand the nature and impact of Nkx2–5 in tumorigenesis

[174]

Nkx2–5 in tumors

Histopathology and Clinical Details

Essential to understand the nature and impact of Nkx2–5 in tumorigenesis

[69]

Transcription factors in Cardiac Myxoma

Human Samples

Explores transcription factors in cardiac myxoma, which aligns with the focus of this study on cardiac myxoma and the role of transcription factors in its development

[70]

Nkx2–5 in cardiogenesis

Histopathology

Potentially shedding light on its influence in cardiac myxoma development

[71]

Nkx2–5 and Oct4: cardiac reprogramming

Histopathology

Provides insights about how these interactions may influence cardiac programming

[72]

Nkx2–5 and Oct4: cardiac reprogramming

Human Samples

Provides insights about how these interactions may influence cardiac programming

[73]

GATA4 in cardiogenesis

Histopathology

Potentially shedding light on its influence in cardiac myxoma development

[74]

GATA4 in cardiogenic potential

Histopathology

Potentially shedding light on its influence in cardiac myxoma development

[75]

GATA4 and its interaction with cyclin D2

Human Samples

Provides insights about how these interactions may influence cardiac programming

[76]

GATA4 and Shh in cardiogenesis

Histopathology

Provides insights about how these interactions may influence cardiac programming

[77]

GATA4 as tumor suppressor

Human Samples

Essential to understand the benign nature of cardiac myxoma

[78]

GATA4 as tumor suppressor

Human Samples

Essential to understand the benign nature of cardiac myxoma

[79]

GATA4 as tumor suppressor

Human Samples

Essential to understand the benign nature of cardiac myxoma

[175]

GATA4 in cardiac repair

Human Samples

To understand the scope of GATA4 in cardiac programming

[176]

GATA4 in cardiac remodeling

Human Samples

To understand the scope of GATA4 in cardiac programming

[177]

GATA4 in activating cardiac gene expression

Histopathology

To understand the scope of GATA4 in cardiac programming

[178]

GATA4 and its tumor suppressor role

Histopathology

Essential to understand the benign nature of cardiac myxoma

[179]

GATA4 in liver tumors

Human Samples

Essential to understand the nature and impact of GATA4 in tumorigenesis

[180]

GATA4 in other tumors

Human Samples

Essential to understand the nature and impact of GATA4 in tumorigenesis

[181]

GATA4 in other tumors

Human Samples

Essential to understand the nature and impact of GATA4 in tumorigenesis

[182]

GATA4 and its interaction with Wnt pathway

Histopathology

Provides insights about how these interactions may influence cardiac programming

[80]

GATA4 in cardiac tumorigenesis

Clinical Details

Relevant to the study’s focus on understanding the origins and mechanisms underlying cardiac myxoma development.

[81]

GATA4 in cardiac tumorigenesis

Histopathology

Relevant to the study’s focus on understanding the origins and mechanisms underlying cardiac myxoma development.

[82]

Tbx5 in stem cells

Human Samples

Aligns with the study’s exploration of Tbx5 and other key cardiac genes/TFs in the context of cardiomyocyte biology and cardiac regeneration

[83]

Tbx5 in stem cells

Human Samples

Aligns with the study’s exploration of Tbx5 and other key cardiac genes/TFs in the context of cardiomyocyte biology and cardiac regeneration

[84]

Tbx5 in cardiogenesis

Histopathology

Aligns with the study’s exploration of Tbx5 and other key cardiac genes/TFs in the context of cardiomyocyte biology and cardiac regeneration

[85]

Mutated Tbx5

Histopathology

To understand the extent of Tbx5 role in governing cardiomyocytes

[86]

Tbx5 in cardiac cell fate

Histopathology

Provides insights about the nature of cardiomyocytes

[87]

Tbx5 and its interaction with mef2c

Histopathology

Provides insights about how these interactions may influence cardiac programming

[88]

Tbx5 and its role as tumor suppressor

Human Samples

Essential to understand the benign nature of cardiac myxoma

[89]

Tbx5 and its dysregulations in cardiogenesis

Histopathology

To understand the extent of Tbx5 role in governing cardiomyocytes

[90]

Mutated Tbx5

Histopathology

To understand the extent of Tbx5 role in governing cardiomyocytes

[91]

Mutated Tbx5

Histopathology

To understand the extent of Tbx5 role in governing cardiomyocytes

[92]

Tbx5 in cardiac differentiation

Histopathology

Provides insights about the limited regenerative capacity of cardiac cells and rare cardiac tumorigenesis

[93]

Tbx5 in cardiac differentiation

Histopathology

Provides insights about the limited regenerative capacity of cardiac cells and rare cardiac tumorigenesis

[94]

Tbx5 in promoting cardiac cell fate

Histopathology

Relevant to understand the role of Tbx5 in cardiac homeostasis

[183]

Tbx5 in cardiac developmental defects

Histopathology

To understand the extent of Tbx5 role in governing cardiomyocytes

[184]

Tbx5 in other tumors

Human Samples

Relevant to the study’s focus on understanding the origins and mechanisms underlying cardiac myxoma development.

[185]

Tbx5 as tumor suppressor

Human Samples

Essential to understand the benign nature of cardiac myxoma

[186]

Tbx5 in other tumors

Human Samples

Relevant to the study’s focus on understanding the origins and mechanisms underlying cardiac myxoma development.

[95]

Tbx5 in inducing cardiac cell fate

Human Samples

Provides insights about the nature of cardiomyocytes

[96]

Tbx5 in cardiac development

Histopathology

Provides insights about the nature of cardiomyocytes

[97]

Mef2c in cardiogenesis

Histopathology

Relevant to understand the proliferative cardiac signaling

[98]

Mef2c in myocardium

Histopathology

Related to interactions with proliferative genes

[99]

Mef2c and its interaction with Nkx2–5

Histopathology

Provides insights about how these interactions may influence cardiac programming

[100]

Mef2c in cardiac development

Histopathology

Potentially shedding light on its influence in cardiac myxoma development

[101]

Mef2c and its interaction with Nkx2–5

Histopathology

Provides insights about how these interactions may influence cardiac programming

[187]

Mef2c in other tumors

Clinical Details

Relevant to the study’s focus on understanding the origins and mechanisms underlying cardiac myxoma development.

[188]

Mef2c in other tumors

Histopathology

Relevant to the study’s focus on understanding the origins and mechanisms underlying cardiac myxoma development.

[189]

Mef2c and its interactions with stemness regulators

Histopathology

Provides insights about progenitor-like state in cardiac myxoma

[190]

Mef2c in other tumors

Histopathology

Essential to understand the its nature and impact on tumorigenesis

[191]

Mef2b in other tumors

Human Samples

Essential to understand the its nature and impact on tumorigenesis

[192]

Mef2b in other tumors

Human Samples

Essential to understand the its nature and impact on tumorigenesis

[102]

Mef2c in cardiac tumorigenesis

Histopathology

Essential to understand the its nature and impact on tumorigenesis

[103]

Mef2c in cardiogenesis

Histopathology

Relevant to cardiac genetic programming

[104]

Mef2c in cardiogenesis

Histopathology

Relevant to cardiac genetic programming

[105]

Mef2c and its interaction with Tbx1

Histopathology

Provides insights about how these interactions may influence cardiac programming

[106]

HAND1/2 in cardiac differentiation

Human Samples

Provides insights about the limited regenerative capacity of cardiac cells and rare cardiac tumorigenesis

[107]

HAND1/2 in cardiogenesis and in heart defects

Histopathology

Relevant to understand its impact on cardiac programing and in different stages of cardiac development

[108]

HAND1/2 in cardiac regeneration

Histopathology

Relevant to understand its impact on cardiac programing and on the limited cardiac regenerative potential

[109]

HAND1/2 in cardiac regeneration

Histopathology

Relevant to understand its impact on cardiac programing and on the limited cardiac regenerative potential

[193]

HAND1/2 in other tumors

Histopathology

Essential to understand the its nature and impact on tumorigenesis

[194]

HAND1/2 as tumor suppressor

Human Samples

Provides insights about rare occurrence of cardiac tumors

[195]

HAND1/2 as tumor suppressor

Histopathology

Provides insights about rare occurrence of cardiac tumors

[196]

HAND1/2 as tumor suppressor

Human Samples

Provides insights about rare occurrence of cardiac tumors

[110]

HAND1/2: Cardiac myxoma showing progenitor-like state

Human Samples

Relevant to understand how HAND1/2 govern the cardiac fate and prevent cardiomyocytes from reverting to progenitor-like state, hallmark of cardiac myxoma

[111]

MYOCD - Cardiogenesis

Histopathology

Aligns with the study’s objective of understanding how MYOCD influences cardiomyocyte biology

[112]

MYOCD in different cell types including cardiomyocytes

Human Samples

Provides insights about different roles it plays in different microenvironments

[113]

MYOCD in stem cells

Histopathology

Provides insights about its influence on the stem cells, to understand the development of progenitor-like state in cardiac myxoma

[197]

MYOCD in cardiac cell fate

Human Samples

Relevant to understand how this gene influences the combinatorial code of cardiomyocytes

[198]

MYOCD in other tumors

Human Samples

Essential to understand the its nature and impact on tumorigenesis

[199]

MYOCD as tumor suppressor

Histopathology

Provides insights about rare occurrence of cardiac tumors

[200]

MYOCD and its interactions

Histopathology

Provides insights about how these interactions may influence cardiac programming

[201]

MYOCD in different tumors

Histopathology

Essential to understand the its nature and impact on tumorigenesis

[202]

MYOCD in different tumors

Histopathology

Essential to understand the its nature and impact on tumorigenesis

[203]

MYOCD and its interactions in promoting cardiogenic potential

Human Samples

Provides insights about how these interactions may influence cardiac programming

[114]

MSX2 and its role in stemness

Histopathology

Provides insights about its influence on the stem cells, to understand the development of progenitor-like state in cardiac myxoma

[115]

MSX2 in cardiac development

Histopathology

Relevant to understand how this gene influences the combinatorial code of cardiomyocytes

[116]

MSX2 and its role in stemness

Human Samples

Provides insights about its influence on the stem cells, to understand the development of progenitor-like state in cardiac myxoma

[204]

MSX2 in promoting stemness

Human Samples

Provides insights about its influence on the stem cells, to understand the development of progenitor-like state in cardiac myxoma

[205]

MSX2 in tumorigenesis

Histopathology

Essential to understand the its nature and impact on tumorigenesis

[206]

MSX2 in other tumors

Histopathology

Essential to understand the its nature and impact on tumorigenesis

[207]

MSX2 in cardiac diseases

Histopathology

Relevant to understand how this gene influences the combinatorial code of cardiomyocytes in diseased states

[208]

MSX2 in other tumors

Human Samples

Essential to understand the its nature and impact on tumorigenesis

[209]

MSX2 and its interaction with other stemness genes

Human Samples

Provides insights about how these interactions may influence cardiac programming

[210]

MSX genes and their impact on apoptosis

Histopathology

Provides insights about rare occurrence of cardiac tumors

[117]

HOPX and its interaction with Wnt and BMPs

Histopathology

Provides insights about how these interactions may influence cardiac programming

[118]

HOPX and its interaction with Nkx2–5

Histopathology

Provides insights about how these interactions may influence cardiac programming

[119]

HOPX in cardiac differentiation

Histopathology

Provides insights about the limited regenerative capacity of cardiac cells and rare cardiac tumorigenesis

[211]

HOPX in other tumors

Human Samples

Essential to understand the its nature and impact on tumorigenesis

[212]

HOPX in other tumors

Histopathology

Essential to understand the its nature and impact on tumorigenesis

[213]

HOPX as tumor suppressor

Human Samples

Provides insights about rare occurrence of cardiac tumors

[120]

Wnt in cardiogenesis

Histopathology

Relevant to the progenitor-like state in cardiac myxoma

[121]

Wnt in cardiac development and disease

Histopathology

Relevant to the progenitor-like state in cardiac myxoma

[122]

Wnt in cardiogenesis

Histopathology

Provides insights about wnt’s impact on the cardiac proliferative potential

[123]

Wnt and its impact on cardiac differentiation

Histopathology

Provides insights about wnt’s impact on limiting the cardiac differentiation and possible impact in the development of progenitor-like state.

[214]

Wnt and its impact on apoptosis

Histopathology

Relevant to the progenitor-like state in cardiac myxoma

[215]

Wnt in different tumors

Histopathology

Essential to understand its nature and impact on tumorigenesis

[216]

Wnt in different tumors

Histopathology

Essential to understand its nature and impact on tumorigenesis

[217]

Wnt in cardiac regeneration

Histopathology

Provides insights about wnt’s impact on the cardiac regenerative potential

[218]

Wnt’s interaction with BMPs

Histopathology

Provides insights about how these interactions may influence cardiac programming

[219]

Wnt’s interaction with Isl1 and FGF

Histopathology

Provides insights about how these interactions may influence cardiac programming

[220]

Wnt in renewal of stem cells

Histopathology

Relevant to the progenitor-like state in cardiac myxoma

[221]

Wnt in dedifferentiation

Human Samples

Relevant to the progenitor-like state in cardiac myxoma

[124]

Wnt in cardiac progenitor cells

Histopathology

Relevant to the progenitor-like state in cardiac myxoma

[125]

Wnt’s interaction with NF-κB

Histopathology

Provides insights about how these interactions may influence cardiac programming

[126]

FGF in heart field

Histopathology

Provides insights about early stages of cardiogenesis

[127]

FGF in heart field

Histopathology

Provides insights about early stages of cardiogenesis

[128]

FGF in cardiogenesis, regeneration and repair

Histopathology

Relevant to understand the limited cardiac regenerative capacity and its impact on the nature of cardiac tumors

[129]

FGF in transitions involved in cardiac development

Histopathology

Relevant to understand the progenitor-like state in cardiac myxoma

[130]

FGF in cardiac differentiation

Histopathology

Provides insights about the cardiac cell-type specific programming

[131]

FGF in cardiomyocyte survival

Histopathology

Relevant to understand the homeostasis in cardiomyocytes

[132]

FGF in stem cells

Histopathology

Relevant to understand the progenitor-like state in cardiac myxoma

[222]

FGF and its interaction with BMPs in heart field

Histopathology

Provides insights about how these interactions may influence cardiac programming

[223]

FGF in postnatal cardioprotection

Histopathology

Relevant to understand the homeostasis in cardiomyocytes

[224]

FGF in preventing pathologic cardiac remodeling

Histopathology

Relevant to understand the homeostasis in cardiomyocytes

[225]

FGF in cardioprotection

Histopathology

Relevant to understand the homeostasis in cardiomyocytes

[226]

FGF and its interactions with other cardiac pathways

Histopathology

Provides insights about how these interactions may influence cardiac programming

[227]

FGF in controlling cardiomyocyte cell cycle

Histopathology

Provides insights about the limited cardiac regenerative capacity

[228]

FGF and its interaction with Nkx2–5

Human Samples

Provides insights about how these interactions may influence cardiac programming

[229]

FGF in cardiac differentiation

Human Samples

Provides insights about the cardiac cell-type specific programming

[133]

FGF expression in cardiac myxoma

Human Samples

Relevant to understand the progenitor-like state in cardiac myxoma

[134]

FGF in cardiac injury

Histopathology

Provides insights about the limited cardiac regenerative capacity

[135]

BMPs in cardiac cell fate

Histopathology

Investigates BMPs in the context of cardiac cell fate

[136]

BMPs in cardiac differentiation

Histopathology

Provides insights about the cardiac cell-type specific programming

[137]

BMPs in cardiac differentiation

Histopathology

Provides insights about the cardiac cell-type specific programming

[138]

BMPs and their interaction with Nkx2–5

Histopathology

Provides insights about how these interactions may influence cardiac programming

[139]

BMPs and their interaction with Nkx2–5

Histopathology

Provides insights about how these interactions may influence cardiac programming

[230]

BMPs in different tumors

Histopathology

Essential to understand its nature and impact on tumorigenesis

[231]

BMPs in cardiac differentiation

Histopathology

Provides insights about the cardiac cell-type specific programming

[232]

BMPs in different tumors

Histopathology

Essential to understand their nature and impact on tumorigenesis

[233]

BMPs in different tumors

Human Samples

Essential to understand their nature and impact on tumorigenesis

[234]

BMPs in mesenchymal stem cells

Human Samples

Relevant to understand the progenitor-like state in cardiac myxoma

[235]

BMPs and their role in progenitor-like state

Histopathology

Relevant to understand the progenitor-like state in cardiac myxoma

[236]

BMPs in tumorigenesis

Human Samples

Essential to understand their nature and impact on tumorigenesis

[237]

BMPs in different tumors

Histopathology

Essential to understand their nature and impact on tumorigenesis

[238]

BMPs in different tumors

Human Samples

Essential to understand their nature and impact on tumorigenesis

[239]

BMPs in promoting tumorigenesis

Human Samples

Essential to understand their nature and impact on tumorigenesis

[240]

BMPs in promoting tumorigenesis

Human Samples

Essential to understand their nature and impact on tumorigenesis

[140]

Notch in lineage commitment and in cardioprotection

Histopathology

Provides insights about the cardiac cell-type specific programming and about the nature of cardiomyocytes

[141]

Notch in cardiac regeneration

Histopathology

Provides insights about the limited cardiac regenerative potential

[142]

Notch in development

Histopathology

Provides insights about the cardiac cell-type specific programming

[143]

Notch in cardiogenesis

Histopathology

Relevant to understand the early stages of cardiac development

[144]

Notch overexpression in oncogenic transformation

Histopathology

Essential to understand its nature and impact on tumorigenesis

[145]

Notch and its interaction with BMPs in cardiogenesis

Histopathology

Provides insights about how these interactions may influence cardiac programming

[146]

Notch signaling in cardiac development and disease

Histopathology

Provides insights about the cardiac cell-type specification in different states

[241]

Notch in promoting stemness

Human Samples

Provides insights about the progenitor-like state in cardiac myxoma

[242]

Notch in controlling the maintenance and commitment of cardiac stem cells

Histopathology

Provides insights about the cardiac cell-type specific programming

[243]

Notch in stemness and tumorigenesis

Human Samples

Provides insights about the progenitor-like state in cardiac myxoma

[244]

Notch and its interaction with Wnt pathway in regulating stemness

Human Samples

Provides insights about how these interactions may influence cardiac programming and contribute to the development of progenitor-like state in cardiac myxoma

[148]

Clinical and molecular features of the Carney complex

Histopathology

Relevant to understand the nature of cardiac myxoma

[149]

PRKAR1A – Carney Complex Mutations

Human Samples

Relevant to understand the nature of cardiac myxoma

[147]

Cardiac myxoma in Carney complex

Clinical Details

Relevant to understand the nature of cardiac myxoma

[150]

Genotype-phenotype correlation for PRKAR1A mutations

Human Samples

Relevant to understand the nature of cardiac myxoma

[151]

Cardiac myxomas in Carney complex

Clinical Details

Relevant to understand the nature of cardiac myxoma

[245]

Endothelial-cardiomyocyte crosstalk in cardioprotection

Histopathology

Relevant to understand the cardiac homeostasis

[246]

Islet1 and GATA4 in cardiac regeneration

Histopathology

Essential in understanding the interactions among the proliferation and differentiation-related genes to understand the genetic landscape of cardiomyocytes

[247]

Cell Generation and Turnover in the Human Heart

Human Samples

Relevant to understand the cardiac homeostasis

[248]

Decline in cardiac regenerative potential

Histopathology

Provides insights about the limited cardiac regenerative potential

[249]

Cardiac gene regulatory programs

Human Samples

Provides insights about the cardiac cell-type specific genetic programming

[250]

Cardiogenesis and cardiac heart defects

Histopathology

Relevant to understand the significance of cardiac cell-type specific genetic programming

[251]

Cardiac cell fate

Human Samples

Provides insights about the cardiac cell-type specific genetic programming

[252]

Microenvironment in cardiac tumor development

Histopathology

Provides insights about the cardiac tumorigenesis

[253]

Cardiac Stem Cell Senescence

Histopathology

Provides insights about the impact of cardiac aging on cardiac cell-type specific genetic programming

[254]

Cardiac Stem Cell Aging

Histopathology

Provides insights about the impact of cardiac aging on cardiac cell-type specific genetic programming

[255]

Regeneration of the aging cardiovascular system

Histopathology

Provides insights about the impact of cardiac aging on cardiac cell-type specific genetic programming

[256]

Gene expression of cancers and its relationship to other diseases

Histopathology

Provides insights about the relationship among different genes involved in tumorigenesis landscape and how they are affected in cell types with limited regenerative capacity

[257]

Cardiac aging

Histopathology

Provides insights about the impact of cardiac aging on cardiac cell-type specific genetic programming

[258]

Cardiac Stem Cells in the Postnatal Heart

Histopathology

Provides insights about cardiac homeostasis

[259]

Cardiac regenerative potential

Histopathology

Relevant to understand the limited cardiac regenerative capacity

[260]

Tumor heterogeneity

Histopathology

Provides insights about tumorigenesis

[261]

Tumor heterogeneity

Histopathology

Provides insights about tumorigenesis

[262]

Tumor heterogeneity and its relation to plasticity

Histopathology

Provides insights about tumorigenesis

[263]

Tumor heterogeneity

Histopathology

Provides insights about tumorigenesis

[264]

Cardiogenesis in congenital heart disease

Histopathology

Provides insights about the cardiac cell-type specific genetic programming in cardiac defects

[265]

Cardiogenesis in congenital heart disease

Histopathology

Provides insights about the cardiac cell-type specific genetic programming in cardiac defects

[152]

Cardiac Reprogramming

Histopathology

Provides insights about the cardiac cell-type specific genetic programming

[266]

Cardiogenesis

Histopathology

Provides insights about the cardiac cell-type specific genetic programming

[267]

Cardiac gene-editing

Histopathology

Provides insights about the new potential therapeutic targets to tackle cardiac diseases

[268]

Gene-editing strategies in cardiovascular cells

Histopathology

Provides insights about the new potential therapeutic targets to tackle cardiac diseases

[269]

Gene-editing in harnessing cardiac regenerative potential

Histopathology

Provides insights about the new potential therapeutic targets to tackle cardiac diseases

[270]

Gene-editing and cardiovascular disease

Histopathology

Provides insights about the new potential therapeutic targets to tackle cardiac diseases

[271]

Gene-editing in cardiac research

Histopathology

Provides insights about the new potential therapeutic targets to tackle cardiac diseases

[272]

Cardiac regeneration

Histopathology

Provides insights about the cardiac cell-type specific genetic programming in relation to cardiac regenerative potential