Table 2 Results of the network meta-analysis (NMA) comparing four treatment regimens simultaneously in terms of the OS, progression-free survival (PFS), objective response rate (ORR) and ≥ 3 grade treatment-related adverse events (≥ 3 TRAEs) are presented. (A) The relative effects, expressed as hazard ratios (HRs) with 95% confidence intervals, are shown for PD-1 + TP; these results demonstrate superiority compared to PD-1 + FP in terms of the PFS and OS. The HRs for a given comparison can be found at the intersection of two treatments. (B) The relative effects, expressed as odds ratios (ORs) with 95% confidence intervals, are presented for PD-1 + TP; in comparison to PD-1 + FP, there is no discernible advantage of PD-1 + TP in terms of the ORR and safety. The ORs for a given comparison can be found at the intersection of two treatments
