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Table 1 In vitro growth inhibition concentration (IC50) (µg/ml) and In vivo estimated LD50 (mg/kg) of ZnONP nanocomposites on EAC tumor cell line

From: Doxorubicin and folic acid-loaded zinc oxide nanoparticles-based combined anti-tumor and anti-inflammatory approach for enhanced anti-cancer therapy

Nanocomposites

In vitro IC50 (µg/ml)

In vivo LD50 (mg/kg)

DOX

6.5

212

ZnONPs

10.8

256

ZnONPs/DOX

20.6

326

ZnONPs/FA

8.3

232

ZnONPs/DOX/FA

38.8

412