Fig. 7

Potentials of ZnONP nanocomposites on the serum level of pro-inflammatory cytokines IL-6 (A) and TNF-α (B) in EAC-challenged mice. EAC-challenged mice IP inoculated with PBS, DOX (0.4 mg), ZnONPs (0.5 mg), ZnONPs/DOX (0.7 mg), ZnONPs/FA (0.5 mg) or ZnONPs /DOX/FA (0.8 mg). Mice were sacrificed on day 11 post tumor challenge and the sera samples were collected. Data were represented as mean ± SD (n = 10). Difference between groups was considered statistically significant at P < 0.05. Note: ^a,b,c Statistically significant difference as compared to the corresponding means of the naive group (a), the EAC group (b), the DOX group (c) within each column