Characteristics | Mirogabalin add-on group (N = 63) | Conventional treatment group (N = 65) |
---|---|---|
Age, years | 67.9 ± 12.4 | 65.7 ± 14.1 |
 ≥ 65 years | 42 (66.7) | 41 (63.1) |
Sex | ||
 Male | 29 (46.0) | 25 (38.5) |
 Female | 34 (54.0) | 40 (61.5) |
BMI, kg/m2 | 22.5 ± 3.3 | 23.8 ± 4.7 |
CrCL, mL/min | 78.0 ± 28.0 | 84.8 ± 40.9 |
 ≥ 60 | 44 (69.8) | 47 (72.3) |
 30 to < 60 | 19 (30.2) | 18 (27.7) |
VAS score at rest, mm | 58.6 ± 13.4 | 57.9 ± 12.4 |
 40 to < 60 | 38 (60.3) | 40 (61.5) |
 ≥ 60 | 24 (38.1) | 25 (38.5) |
Duration from lung resection to chest drain removal, days | 2.7 ± 2.1 | 2.6 ± 1.8 |
 Median (Q1, Q3) | 2.0 (1.0, 3.0) | 2.0 (2.0, 3.0) |
Duration from chest drain removal to registration | ||
 1 day | 46 (73.0) | 50 (76.9) |
 2 days | 17 (27.0) | 15 (23.1) |
Duration from lung resection to discharge, days | 9.2 ± 4.8 | 17.2 ± 49.8 |
 Median (Q1, Q3) | 8.0 (6.0, 10.0) | 7.0 (6.0, 9.0) |
Approach method | ||
 Thoracotomy | 28 (44.4) | 20 (30.8) |
 VATS | 25 (39.7) | 36 (55.4) |
 Robotic | 10 (15.9) | 9 (13.8) |
Use of rib spreader | 28 (44.4) | 20 (30.8) |
Diagnosis at admission | ||
 Primary lung cancer | 54 (85.7) | 49 (75.4) |
 Metastatic lung cancer | 6 (9.5) | 3 (4.6) |
 Mediastinal tumor | 0 (0.0) | 2 (3.1) |
 Pneumothorax | 1 (1.6) | 1 (1.5) |
 Other | 2 (3.2) | 10 (15.4) |
Operation time, min | 188.5 ± 79.0 | 189.3 ± 64.8 |
 Median (Q1, Q3) | 183.0 (143.0, 221.0) | 182.0 (154.0, 229.0) |
Blood loss | ||
 ≤ 10 mL | 30 (47.6) | 32 (49.2) |
 > 10 to ≤ 100 mL | 23 (36.5) | 25 (38.5) |
 > 100 to ≤ 200 mL | 4 (6.3) | 3 (4.6) |
 > 200 to ≤ 300 mL | 1 (1.6) | 1 (1.5) |
 > 300 mL | 5 (7.9) | 4 (6.2) |
Maximum wound size, cm | 6.7 ± 4.0 | 6.5 ± 4.6 |
 Median (Q1, Q3) | 6.0 (4.0, 8.0) | 5.0 (4.0, 8.0) |
aNSAID | 44 (69.8) | 50 (76.9) |
aAcetaminophen | 36 (57.1) | 51 (78.5) |