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Fig. 10 | BMC Cancer

Fig. 10

From: Integrative analysis of transcriptomic and metabolomic profiles reveals enhanced arginine metabolism in androgen-independent prostate cancer cells

Fig. 10

Correlation analysis between differentially expressed metabolites and genes. A Heatmap illustrating the correlation between differentially expressed metabolites and genes. The horizontal and vertical axes represent the differentially expressed genes and metabolites used for analysis, respectively. The color of each heatmap block indicates the correlation coefficient obtained through Pearson correlation analysis: red indicates a positive correlation, blue indicates a negative correlation. * denotes a significant correlation between key species and metabolites (p-value<0.05), and ** denotes an extremely significant correlation (p-value<0.01). B Network representation showing the correlation between differentially expressed metabolites (blue nodes) and genes (red nodes). The size of each node reflects its degree of centrality, indicating the number of connections it has with other nodes. The thickness of the lines in the network is determined by the rho value, which indicates the strength of the correlation (absolute value of rho): thicker lines represent stronger correlations (positive or negative), while thinner lines represent weaker correlations. Solid gold lines represent positive correlations, while dashed silver lines represent negative correlations

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