Fig. 1

Volcano map of DEGs between LNCaP-ADR cells and LNCaP parental cells. The volcano map displays the differentially expressed genes (DEGs) between LNCaP-ADR cells (LA group) and LNCaP parental cells (L group). The x-axis is presented on a log2 scale, representing the fold change in gene expression between LNCaP-ADR cells and LNCaP parental cells (log2(fold change)). Negative values on the x-axis indicate downregulation, whereas positive values indicate upregulation. The y-axis is presented on a log10 scale, depicting the p-values, which determine the significance level of expression difference. Red dots on the volcano map indicate significantly upregulated genes with at least a two-fold change, while blue dots represent significantly downregulated genes, also with at least a two-fold change