High SNHG expression may predict a poor lung cancer prognosis based on a meta-analysis

BMC Cancer

Table 3 Pooled HRs of overall survival of patients with increased SNHG expression

	No. of studies	No. of patients	Pooled HR (95% CI)		Heterogeneity
	No. of studies	No. of patients	Fixed	Random	I²(%)	P-value
OS	30	1748	1.890 (1.595–2.185)	1.89 (1.595–2.185)	0	0.98
Cut-off value
Median	12	644	1.643 (1.262–2.024)	1.643 (1.262–2.024)	0	0.847
Mean	17	1062	2.262 (1.790–2.734)	2.262 (1.790–2.734)	0	0.995
Not reported	1	42	2.160 (-0.665–4.985)	2.160 (-0.665–4.985)	-	-
Analysis method
Multivariate analysis	3	247	2.793 (1.631–3.955)	2.793 (1.631–3.955)	0	0.734
Univariate analysis	27	1501	1.828 (1.523–2.133)	1.828 (1.523–2.133)	0	0.988
Number of patients
Less than 100	27	1382	2.159 (1.783–2.534)	2.159 (1.783–2.534)	0	1
Not less than 100	3	366	1.457 (0.980–1.933)	1.873 (0.764–2.982)	48.6	0.143
Follow-up (month)
Not less than 60 month	22	1319	1.819 (1.503–2.135)	1.819 (1.503–2.135)	0	0.962
Less than 60 month	8	429	2.373 (1.550–3.197)	2.373 (1.550–3.197)	0	0.885
NOS score
9	3	247	2.793 (1.631–3.955)	2.793 (1.631–3.955)	0	0.734
Less than 9	27	1501	1.828 (1.523–2.133)	1.828 (1.523–2.133)	0	0.988

OS Overall survival, Random Random effects, Fixed Fixed effects, directly HR was extracted directly from the primary articles, indirectly HR was extracted indirectly from the primary articles, CI Confidence interval

ISSN: 1471-2407